25. EFFECT OF STEREOTACTIC RADIOSURGERY COMPARED TO WHOLE-BRAIN RADIOTHERAPY FOR LIMITED BRAIN METASTASIS ON LONG TERM COGNITION AND QUALITY OF LIFE: A POOLED ANALYSIS OF NCCTG N107C/CEC.3 AND N0574 (ALLIANCE) RANDOMIZED CLINICAL TRIALS

PURPOSE: We investigated the long term impact of SRS and WBRT in two large prospective phase III trials. METHODS: Patients with 1–4 BMs +/- resection were randomized to SRS or WBRT. Cognitive deterioration was a drop of >1 standard deviation from baseline in >2/6 cognitive measures (CM). Quali...

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Detalles Bibliográficos
Autores principales: Palmer, Joshua, Klamer, Brett, Ballman, Karla, Brown, Paul, Cerhan, Jane, Anderson, Keith, Whitton, Anthony, Greenspoon, Jeffrey, Chung, Caroline, Burri, Stuart, Parney, Ian, Stieber, Volker, Pollock, Bruce, Laack, Nadia, Ashman, Jonathon, Bahary, Jean-Paul, Barker, Fred, Galanis, Evanthia, Asher, Anthony, Roberge, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401389/
http://dx.doi.org/10.1093/noajnl/vdaa073.015

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