62. PRESENCE OF EXTRACRANIAL TUMORS INFLUENCES RESPONSE TO IMMUNE CHECKPOINT INHIBITORS IN A PRE-CLINICAL MODEL OF MELANOMA BRAIN METASTASIS

Up to 75% of patients with melanoma develop brain metastases. While immune checkpoint inhibitors (ICI) targeting PD-1 and CTLA4 have revolutionized the treatment of metastatic melanoma, responses within the immune-specialized microenvironment of the brain are not well understood and there is a pauci...

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Detalles Bibliográficos
Autores principales: Nayyar, Naema, Singh, Mohini, Stocking, Jackson, Brehm, Michael, Brastianos, Priscilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401395/
http://dx.doi.org/10.1093/noajnl/vdaa073.050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401395/
http://dx.doi.org/10.1093/noajnl/vdaa073.050

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