20. MELANOMA CELL INTRINSIC GABAA RECEPTOR ENHANCEMENT POTENTIATES RADIATION AND IMMUNE CHECKPOINT INHIBITOR RESPONSE BY PROMOTING DIRECT AND T CELL-MEDIATED ANTI-TUMOR ACTIVITY

Most metastatic melanoma patients exhibit poor and variable response to radiotherapy and targeted therapies, including immune checkpoint inhibitors. There is a need for therapeutics that can potentiate existing treatments to positively impact clinical outcomes of metastatic melanoma patients. We rea...

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Detalles Bibliográficos
Autores principales: Sengupta, Soma, Nasti, Tahseen, Kaluzova, Milota, Kallay, Laura, Melms, Johannes, Izar, Benjamin, Xu, Maxwell, Bhattacharya, Debanjan, Burnham, Andre, Li, Guanguan, Ahmed, Taukir, Lawson, David, Kowalski, Jeanne, Cook, James, Medvedovic, Mario, Jenkins, Andrew, Khan, Mohammad, Pomeranz Krummel, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401396/
http://dx.doi.org/10.1093/noajnl/vdaa073.010

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