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The Role of Hypoxia-Inducible Factor 1α in the Regulation of Human Meibomian Gland Epithelial Cells

PURPOSE: We recently discovered that a hypoxic environment is beneficial for meibomian gland (MG) function. The mechanisms underlying this effect are unknown, but we hypothesize that it is due to an increase in the levels of hypoxia-inducible factor 1α (HIF1α). In other tissues, HIF1α is the primary...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Wang, Jingyi, Chen, Di, Kam, Wendy R., Sullivan, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401459/
https://www.ncbi.nlm.nih.gov/pubmed/32150252
http://dx.doi.org/10.1167/iovs.61.3.1