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The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes
PURPOSE: The purpose of this study was to analyze the clinical features of dome-shaped macula (DSM) in highly myopic eyes and its morphological relationship with myopic retinoschisis (MRS). METHODS: In this cross-sectional study, 409 eyes of 409 patients with high myopia who had spectral-domain opti...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401483/ https://www.ncbi.nlm.nih.gov/pubmed/32176269 http://dx.doi.org/10.1167/iovs.61.3.19 |
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author | Fang, Dong Zhang, Zhaotian Wei, Yantao Wang, Li Zhang, Ting Jiang, Xintong Shi, Yunhong Zhang, Shaochong |
author_facet | Fang, Dong Zhang, Zhaotian Wei, Yantao Wang, Li Zhang, Ting Jiang, Xintong Shi, Yunhong Zhang, Shaochong |
author_sort | Fang, Dong |
collection | PubMed |
description | PURPOSE: The purpose of this study was to analyze the clinical features of dome-shaped macula (DSM) in highly myopic eyes and its morphological relationship with myopic retinoschisis (MRS). METHODS: In this cross-sectional study, 409 eyes of 409 patients with high myopia who had spectral-domain optical coherence tomography (OCT) examinations were included. The associations of DSM with the distribution of MRS and ocular biometry were evaluated. RESULTS: Of 409 eyes, DSM was detected in 64 eyes (15.6%). The eyes with DSM were more myopic (−18.8 ± 3.9 vs. −13.4 ± 5.9; P < 0.001) and had longer axial length (31.7 ± 2.4 vs. 29.5 ± 2.5; P < 0.001) compared with those without DSM. A higher rate of extrafoveal retinoschisis (35.9% vs. 9.6%; P < 0.001) and a lower rate of foveoschisis (10.9% vs. 26.1%; P = 0.01) were detected in the eyes with DSM compared with those without DSM. In the eyes with DSM, MRS was detected in 30 eyes (46.9%). MRS predominantly affected the extrafoveal area (76.7%), especially the base of the dome (82.6%). The extrafoveal retinoschisis was most frequently distributed in the superior quadrant (52.2%). None of the eyes with DSM displayed fovea-only retinoschisis. The ratio of the height and width of the macular bulge was higher in eyes with MRS than those without MRS (0.05 vs. 0.04; P = 0.001). CONCLUSIONS: A DSM is found in highly myopic eyes with a longer axial length. MRS in eyes with DSM is more likely to affect the extrafoveal area, especially the base of the dome. A steeper macular bulge is associated with the occurrence of MRS. |
format | Online Article Text |
id | pubmed-7401483 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Association for Research in Vision and Ophthalmology |
record_format | MEDLINE/PubMed |
spelling | pubmed-74014832020-08-18 The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes Fang, Dong Zhang, Zhaotian Wei, Yantao Wang, Li Zhang, Ting Jiang, Xintong Shi, Yunhong Zhang, Shaochong Invest Ophthalmol Vis Sci Retina PURPOSE: The purpose of this study was to analyze the clinical features of dome-shaped macula (DSM) in highly myopic eyes and its morphological relationship with myopic retinoschisis (MRS). METHODS: In this cross-sectional study, 409 eyes of 409 patients with high myopia who had spectral-domain optical coherence tomography (OCT) examinations were included. The associations of DSM with the distribution of MRS and ocular biometry were evaluated. RESULTS: Of 409 eyes, DSM was detected in 64 eyes (15.6%). The eyes with DSM were more myopic (−18.8 ± 3.9 vs. −13.4 ± 5.9; P < 0.001) and had longer axial length (31.7 ± 2.4 vs. 29.5 ± 2.5; P < 0.001) compared with those without DSM. A higher rate of extrafoveal retinoschisis (35.9% vs. 9.6%; P < 0.001) and a lower rate of foveoschisis (10.9% vs. 26.1%; P = 0.01) were detected in the eyes with DSM compared with those without DSM. In the eyes with DSM, MRS was detected in 30 eyes (46.9%). MRS predominantly affected the extrafoveal area (76.7%), especially the base of the dome (82.6%). The extrafoveal retinoschisis was most frequently distributed in the superior quadrant (52.2%). None of the eyes with DSM displayed fovea-only retinoschisis. The ratio of the height and width of the macular bulge was higher in eyes with MRS than those without MRS (0.05 vs. 0.04; P = 0.001). CONCLUSIONS: A DSM is found in highly myopic eyes with a longer axial length. MRS in eyes with DSM is more likely to affect the extrafoveal area, especially the base of the dome. A steeper macular bulge is associated with the occurrence of MRS. The Association for Research in Vision and Ophthalmology 2020-03-16 /pmc/articles/PMC7401483/ /pubmed/32176269 http://dx.doi.org/10.1167/iovs.61.3.19 Text en Copyright 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
spellingShingle | Retina Fang, Dong Zhang, Zhaotian Wei, Yantao Wang, Li Zhang, Ting Jiang, Xintong Shi, Yunhong Zhang, Shaochong The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes |
title | The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes |
title_full | The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes |
title_fullStr | The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes |
title_full_unstemmed | The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes |
title_short | The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes |
title_sort | morphological relationship between dome-shaped macula and myopic retinoschisis: a cross-sectional study of 409 highly myopic eyes |
topic | Retina |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401483/ https://www.ncbi.nlm.nih.gov/pubmed/32176269 http://dx.doi.org/10.1167/iovs.61.3.19 |
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