Cargando…

Aminoguanidine inhibits IL-1β-induced protein expression of iNOS and COX-2 by blocking the NF-κB signaling pathway in rat articular chondrocytes

Osteoarthritis is a chronic joint disease which has a serious impact on the health and quality of life of affected humans and animals. As an inhibitor of inducible nitric oxide synthase (iNOS), aminoguanidine (AG) displays anti-inflammatory effects. The purpose of the present study was to investigat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Yuanqiang, Song, Xiaopeng, Ma, Tianwen, Li, Yue, Bai, Hui, Zhang, Zhiheng, Hu, Hailong, Yuan, Rui, Wen, Yajing, Gao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401635/
https://www.ncbi.nlm.nih.gov/pubmed/32765755
http://dx.doi.org/10.3892/etm.2020.9021