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Downregulation of microRNA-224-3p Hampers Retinoblastoma Progression via Activation of the Hippo-YAP Signaling Pathway by Increasing LATS2

PURPOSE: The pivotal role of microRNAs (miRNAs or miRs) has been proved in the pathogenesis of retinoblastoma. miR-224-3p is demonstrated to be involved in several tumors. However, the underlying mechanism of miR-224-3p in retinoblastoma is yet to be investigated. Therefore, this study was designed...

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Detalles Bibliográficos
Autores principales: Song, Lili, Huang, Yanxia, Zhang, Xinli, Han, Shaoping, Hou, Min, Li, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401717/
https://www.ncbi.nlm.nih.gov/pubmed/32186675
http://dx.doi.org/10.1167/iovs.61.3.32