Cargando…

The Potential Inhibitory Effects of miR-19b on Ocular Inflammation are Mediated Upstream of the JAK/STAT Pathway in a Murine Model of Allergic Conjunctivitis

PURPOSE: Thymic stromal lymphopoietin (TSLP) is a pro-allergic cytokine that initiates allergic inflammatory reaction between epithelial and dendritic cells (DCs). miR-19b was reported to suppress TSLP expression. The present study aimed to examine miR-19b expression, regulation, and function in all...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Chen, Liu, Jinghua, Hao, Peng, Wang, Yuchuan, Sui, Shuangshuang, Li, Linghan, Ying, Ming, Han, Ruifang, Wang, Liming, Li, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401772/ https://www.ncbi.nlm.nih.gov/pubmed/32150250 http://dx.doi.org/10.1167/iovs.61.3.8

Ejemplares similares

IFN-γ Facilitates Corneal Epithelial Cell Pyroptosis Through the JAK2/STAT1 Pathway in Dry Eye
por: Yang, Xue, et al.
Publicado: (2023)

TSLP Produced by Aspergillus fumigatus-Stimulated DCs Promotes a Th17 Response Through the JAK/STAT Signaling Pathway in Fungal Keratitis
por: Han, Fang, et al.
Publicado: (2020)

Inflammatory Response to Lipopolysaccharide on the Ocular Surface in a Murine Dry Eye Model
por: Simmons, Ken T., et al.
Publicado: (2016)

Mesenchymal Stromal Cells Inhibit Neutrophil Effector Functions in a Murine Model of Ocular Inflammation
por: Mittal, Sharad K., et al.
Publicado: (2018)

Enzymatic Resistance of Corneas Crosslinked Using Riboflavin in Conjunction With Low Energy, High Energy, and Pulsed UVA Irradiation Modes
por: Aldahlawi, Nada H., et al.
Publicado: (2016)

Dysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide
por: Wang, Changjun, et al.
Publicado: (2019)

ACE2 Expression Is Upregulated in Inflammatory Corneal Epithelial Cells and Attenuated by Resveratrol
por: Jiang, Zhixin, et al.
Publicado: (2021)

Mast Cells Initiate the Recruitment of Neutrophils Following Ocular Surface Injury
por: Sahu, Srikant K., et al.
Publicado: (2018)

Modulating Ocular Surface Pain Through Neurokinin-1 Receptor Blockade
por: Lasagni Vitar, Romina Mayra, et al.
Publicado: (2021)

PEDF Gene Deletion Disrupts Corneal Innervation and Ocular Surface Function
por: Shang, Zhenying, et al.
Publicado: (2021)

Diabetes-Associated Hyperglycemia Causes Rapid-Onset Ocular Surface Damage
por: Weng, Judy, et al.
Publicado: (2023)

Interleukin-11 Suppresses Ocular Surface Inflammation and Accelerates Wound Healing
por: Singh, Aastha, et al.
Publicado: (2023)

A Novel Murine Model of Radiation Keratopathy
por: Harris, Deshea L., et al.
Publicado: (2018)

Molecular and Phenotypic Characterization of Ocular Methicillin-Resistant Staphylococcus epidermidis Isolates in Taiwan
por: Chang, Yin-Hsi, et al.
Publicado: (2023)

Measuring corneal hysteresis: threshold estimation of the waveform score from the Ocular Response Analyzer
por: Ayala, Marcelo, et al.
Publicado: (2012)

Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development
por: Seo, Seungwoon, et al.
Publicado: (2017)

Effect of High Glucose on Ocular Surface Epithelial Cell Barrier and Tight Junction Proteins
por: Alfuraih, Saleh, et al.
Publicado: (2020)

Effects of Mirogabalin on Hyperalgesia and Chronic Ocular Pain in Tear-Deficient Dry-Eye Rats
por: Kikuchi, Kasumi, et al.
Publicado: (2023)

Alteration of Meibum Lipidomics Profiling in Patients With Chronic Ocular Graft-Versus-Host Disease
por: Zhao, Wenxin, et al.
Publicado: (2023)

Reduced Levels of Tear Lacritin Are Associated With Corneal Neuropathy in Patients With the Ocular Component of Sjögren's Syndrome
por: McNamara, Nancy A., et al.
Publicado: (2016)

Gp130 Promotes Inflammation via the STAT3/JAK2 Pathway in Allergic Conjunctivitis
por: Bao, Jiayu, et al.
Publicado: (2023)

Generation of Human Corneal Endothelial Cells via In Vitro Ocular Lineage Restriction of Pluripotent Stem Cells
por: Zhao, Jiagang J., et al.
Publicado: (2016)

Spectrum and resistance in bacterial infections of the ocular surface in a German tertiary referral center 2009–2019
por: Roth, Mathias, et al.
Publicado: (2022)

PPAR-α Agonist Fenofibrate Suppressed the Formation of Ocular Surface Squamous Metaplasia Induced by Topical Benzalkonium Chloride
por: He, Huan, et al.
Publicado: (2020)

Differential Distribution of Laminin N-Terminus α31 Across the Ocular Surface: Implications for Corneal Wound Repair
por: Barrera, Valentina, et al.
Publicado: (2018)

Functional Changes of the Ocular Surface Sensory Nerves Due to Contact Lens Use in Young Symptomatic and Asymptomatic Users
por: Pastor-Zaplana, José Ángel, et al.
Publicado: (2023)

Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea
por: Díaz, Nicolás M., et al.
Publicado: (2020)

Stemness and Regenerative Potential of Corneal Stromal Stem Cells and Their Secretome After Long-Term Storage: Implications for Ocular Regeneration
por: Kumar, Ajay, et al.
Publicado: (2018)

Outcomes and complications of cataract surgery in patients with chronic ocular graft-versus-host-disease—a multicenter, retrospective analysis
por: Gehlsen, Uta, et al.
Publicado: (2022)

Association of Ocular Surface Immune Cells With Dry Eye Signs and Symptoms in the Dry Eye Assessment and Management (DREAM) Study
por: Kuklinski, Eric J., et al.
Publicado: (2023)

A Method for Real-Time Assessment of Mitochondrial Respiration Using Murine Corneal Biopsy
por: Liang, Wentao, et al.
Publicado: (2023)

Ambient Air Currents Activate Corneal Nerves During Ocular Desiccation in Rats: Simultaneous Recordings of Neural Activity and Corneal Temperature
por: Hirata, Harumitsu, et al.
Publicado: (2018)

KLF4 Coordinates Corneal Epithelial Apical-Basal Polarity and Plane of Cell Division and Is Downregulated in Ocular Surface Squamous Neoplasia
por: Tiwari, Anil, et al.
Publicado: (2020)

Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease
por: Tahmaz, Volkan, et al.
Publicado: (2020)

Bacillus-Derived Manganese Superoxide Dismutase Relieves Ocular-Surface Inflammation and Damage by Reducing Oxidative Stress and Apoptosis in Dry Eye
por: Yoon, Hyeon-Jeong, et al.
Publicado: (2023)

Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren's Syndrome
por: Shah, Mihir, et al.
Publicado: (2017)

Elevated levels of prostaglandin E(2) in the tears of patients with severe allergic conjunctivitis and primary cultured conjunctival cells are suppressed by ketotifen and dexamethasone
por: Yamanishi, Ryutaro, et al.
Publicado: (2021)

Different Murine High-Risk Corneal Transplant Settings Vary Significantly in Their (Lymph)angiogenic and Inflammatory Cell Signatures
por: Zhang, Wei, et al.
Publicado: (2022)

The Chemokine Receptor CXCR4 Mediates Recruitment of CD11c(+) Conventional Dendritic Cells Into the Inflamed Murine Cornea
por: Lopez, Maria J., et al.
Publicado: (2018)

High-Fat Diet Induces Inflammation of Meibomian Gland
por: Bu, Jinghua, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_puba9mo00kqg1rho2lf9b9nce9