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Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation
Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton and transduce signals in response to both chemical and mechanical cues. The composition, interactions, stoichiometry, and topological organization of proteins within IACs are not fully understood. To address...
Autores principales: | Chastney, Megan R., Lawless, Craig, Humphries, Jonathan D., Warwood, Stacey, Jones, Matthew C., Knight, David, Jorgensen, Claus, Humphries, Martin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401799/ https://www.ncbi.nlm.nih.gov/pubmed/32585685 http://dx.doi.org/10.1083/jcb.202003038 |
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