Rashomon at the kinetochore: Function(s) of the Mad1–cyclin B1 complex

In the film Rashomon, four witnesses describe seemingly contradictory views of one event. In a recent analogy, an interaction between the master mitotic regulator cyclin B1 and the spindle checkpoint component Mad1 was independently described by three groups who propose strikingly different function...

Descripción completa

Detalles Bibliográficos
Autores principales: Houston, Jack, Lara-Gonzalez, Pablo, Desai, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401815/
https://www.ncbi.nlm.nih.gov/pubmed/32614383
http://dx.doi.org/10.1083/jcb.202006006
_version_ 1783566636711673856
author Houston, Jack
Lara-Gonzalez, Pablo
Desai, Arshad
author_facet Houston, Jack
Lara-Gonzalez, Pablo
Desai, Arshad
author_sort Houston, Jack
collection PubMed
description In the film Rashomon, four witnesses describe seemingly contradictory views of one event. In a recent analogy, an interaction between the master mitotic regulator cyclin B1 and the spindle checkpoint component Mad1 was independently described by three groups who propose strikingly different functions for this interaction. Here, we summarize their findings and present a perspective on reconciling the different views.
format Online
Article
Text
id pubmed-7401815
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-74018152021-02-03 Rashomon at the kinetochore: Function(s) of the Mad1–cyclin B1 complex Houston, Jack Lara-Gonzalez, Pablo Desai, Arshad J Cell Biol Viewpoint In the film Rashomon, four witnesses describe seemingly contradictory views of one event. In a recent analogy, an interaction between the master mitotic regulator cyclin B1 and the spindle checkpoint component Mad1 was independently described by three groups who propose strikingly different functions for this interaction. Here, we summarize their findings and present a perspective on reconciling the different views. Rockefeller University Press 2020-07-02 /pmc/articles/PMC7401815/ /pubmed/32614383 http://dx.doi.org/10.1083/jcb.202006006 Text en © 2020 Houston et al. http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Viewpoint
Houston, Jack
Lara-Gonzalez, Pablo
Desai, Arshad
Rashomon at the kinetochore: Function(s) of the Mad1–cyclin B1 complex
title Rashomon at the kinetochore: Function(s) of the Mad1–cyclin B1 complex
title_full Rashomon at the kinetochore: Function(s) of the Mad1–cyclin B1 complex
title_fullStr Rashomon at the kinetochore: Function(s) of the Mad1–cyclin B1 complex
title_full_unstemmed Rashomon at the kinetochore: Function(s) of the Mad1–cyclin B1 complex
title_short Rashomon at the kinetochore: Function(s) of the Mad1–cyclin B1 complex
title_sort rashomon at the kinetochore: function(s) of the mad1–cyclin b1 complex
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401815/
https://www.ncbi.nlm.nih.gov/pubmed/32614383
http://dx.doi.org/10.1083/jcb.202006006
work_keys_str_mv AT houstonjack rashomonatthekinetochorefunctionsofthemad1cyclinb1complex
AT laragonzalezpablo rashomonatthekinetochorefunctionsofthemad1cyclinb1complex
AT desaiarshad rashomonatthekinetochorefunctionsofthemad1cyclinb1complex

Ejemplares similares