UV-B-Induced Inflammasome Activation Can Be Prevented by Cis-Urocanic Acid in Human Corneal Epithelial Cells

PURPOSE: The cornea is continually exposed to highly energetic solar UV-B (280-320 nm). Our aim was to investigate whether UV-B triggers the activation of NLRP3 inflammasomes and the production of IL-1β and/or IL-18 in human corneal epithelial (HCE) cells. Additionally, we studied the capability of...

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Detalles Bibliográficos
Autores principales: Korhonen, Eveliina, Bisevac, Jovana, Hyttinen, Juha M. T., Piippo, Niina, Hytti, Maria, Kaarniranta, Kai, Petrovski, Goran, Kauppinen, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401861/
https://www.ncbi.nlm.nih.gov/pubmed/32271889
http://dx.doi.org/10.1167/iovs.61.4.7

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