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High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy
PURPOSE: To determine whether high glucose (HG) compromises internalization of lysyl oxidase (LOX) through excess binding of LOX with extracellular matrix (ECM) proteins. METHODS: To determine whether HG promotes binding of LOX with ECM proteins, fibronectin (FN) and collagen IV (Coll IV), total or...
Autores principales: | Nguyen, Ngan-Ha, Kim, Dongjoon, Roy, Sayon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401919/ https://www.ncbi.nlm.nih.gov/pubmed/32340032 http://dx.doi.org/10.1167/iovs.61.4.40 |
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