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KDM6A suppresses hepatocellular carcinoma cell proliferation by negatively regulating the TGF-β/SMAD signaling pathway

Lysine demethylase 6A (KDM6A) is a Jumonji-C domain-containing histone demethylase that specifically catalyzes the removal of histone H3 lysine-27 trimethylation. KDM6A is a member of the KDM6 family, the biological role of which has been reported in various types of cancer, including bladder and lu...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Yang, Jing, Zhang, Xin, Liu, Hong, Guo, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401926/
https://www.ncbi.nlm.nih.gov/pubmed/32765772
http://dx.doi.org/10.3892/etm.2020.9000