Cargando…

KDM6A suppresses hepatocellular carcinoma cell proliferation by negatively regulating the TGF-β/SMAD signaling pathway

Lysine demethylase 6A (KDM6A) is a Jumonji-C domain-containing histone demethylase that specifically catalyzes the removal of histone H3 lysine-27 trimethylation. KDM6A is a member of the KDM6 family, the biological role of which has been reported in various types of cancer, including bladder and lu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yuan, Yang, Jing, Zhang, Xin, Liu, Hong, Guo, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401926/ https://www.ncbi.nlm.nih.gov/pubmed/32765772 http://dx.doi.org/10.3892/etm.2020.9000

Ejemplares similares

The effect of propofol on the proliferation and apoptosis of hepatocellular carcinoma cells through TGF-Β1/Smad2 signaling pathway
por: Li, Zongchao, et al.
Publicado: (2021)

An inhibitory role of NEK6 in TGFβ/Smad signaling pathway
por: Zuo, Jie, et al.
Publicado: (2015)

Upregulation of miR-101a Suppresses Chronic Renal Fibrosis by Regulating KDM3A via Blockade of the YAP-TGF-β-Smad Signaling Pathway
por: Ding, Hong, et al.
Publicado: (2020)

Inhibition of Wilms' Tumor Proliferation and Invasion by Blocking TGF-β Receptor I in the TGF-β/Smad Signaling Pathway
por: Shi, Qinlin, et al.
Publicado: (2020)

β-Sitosterol Inhibits The Proliferation of Endometrial Cells via Regulating Smad7-Mediated TGF-β/Smads Signaling Pathway
por: Wen, Yi, et al.
Publicado: (2023)

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

Bioflavonoid Galangin Suppresses Hypertrophic Scar Formation by the TGF-β/Smad Signaling Pathway
por: Ru, Zha, et al.
Publicado: (2021)

Pirfenidone suppressed triple‐negative breast cancer metastasis by inhibiting the activity of the TGF‐β/SMAD pathway
por: Luo, Daiqin, et al.
Publicado: (2023)

NIT1 suppresses tumour proliferation by activating the TGFβ1–Smad2/3 signalling pathway in colorectal cancer
por: Lin, Chun, et al.
Publicado: (2018)

MicroRNA-362 negatively and positively regulates SMAD4 expression in TGF-β/SMAD signaling to suppress cell migration and invasion
por: Cheng, Han Ping, et al.
Publicado: (2021)

Roles of TGFβ signaling Smads in squamous cell carcinoma
por: Han, Gangwen, et al.
Publicado: (2011)

Berberine Suppresses EMT in Liver and Gastric Carcinoma Cells through Combination with TGFβR Regulating TGF-β/Smad Pathway
por: Du, Haiyan, et al.
Publicado: (2021)

Endothelial Nogo-B Suppresses Cancer Cell Proliferation via a Paracrine TGF-β/Smad Signaling
por: Li, Hengyu, et al.
Publicado: (2022)

NANOG regulates the proliferation of PCSCs via the TGF-β1/SMAD pathway
por: Liu, Changming, et al.
Publicado: (2020)

Magnolol Suppresses Pancreatic Cancer Development In Vivo and In Vitro via Negatively Regulating TGF-β/Smad Signaling
por: Chen, Shuo, et al.
Publicado: (2020)

Organ microenvironment affects growth and metastasis of hepatocellular carcinoma via the TGF-β/Smad pathway in mice
por: LI, GUOCAI, et al.
Publicado: (2013)

Downregulation of CR6-interacting factor 1 suppresses keloid fibroblast growth via the TGF-β/Smad signaling pathway
por: Nagar, Harsha, et al.
Publicado: (2021)

Comparative Analysis of TGF-β/Smad Signaling Dependent Cytostasis in Human Hepatocellular Carcinoma Cell Lines
por: Dzieran, Johanna, et al.
Publicado: (2013)

A Water-Soluble Hydrogen Sulfide Donor Suppresses the Growth of Hepatocellular Carcinoma via Inhibiting the AKT/GSK-3β/β-Catenin and TGF-β/Smad2/3 Signaling Pathways
por: Duan, Shao-Feng, et al.
Publicado: (2023)

Tranilast Inhibits Pulmonary Fibrosis by Suppressing TGFβ/SMAD2 Pathway
por: Kato, Motoyasu, et al.
Publicado: (2020)

let-7a suppresses liver fibrosis via TGFβ/SMAD signaling transduction pathway
por: Zhang, Yinghui, et al.
Publicado: (2019)

Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways
por: Geng, Xiao-qiang, et al.
Publicado: (2019)

TGF-β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway
por: He, Dengwei, et al.
Publicado: (2021)

Inhibition of keloid by (32)P isotope radiotherapy through suppressing TGF-β/Smad signaling pathway
por: Xie, Long, et al.
Publicado: (2023)

Matrine Suppresses Pancreatic Fibrosis by Regulating TGF-β/Smad Signaling in Rats
por: Liu, Pi, et al.
Publicado: (2019)

pVHL-mediated SMAD3 degradation suppresses TGF-β signaling
por: Zhou, Jun, et al.
Publicado: (2021)

Aspirin attenuates liver fibrosis by suppressing TGF-β1/Smad signaling
por: Sun, Yimin, et al.
Publicado: (2022)

Iodine-125 Seeds Inhibit Carcinogenesis of Hepatocellular Carcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via TGF-β1/Smad Signaling
por: Yang, Chongshuang, et al.
Publicado: (2022)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

Homeobox B9 Promotes the Progression of Hepatocellular Carcinoma via TGF-β1/Smad and ERK1/2 Signaling Pathways
por: Bai, Lizhi, et al.
Publicado: (2022)

Correction: Comparative Analysis of TGF-β/Smad Signaling Dependent Cytostasis in Human Hepatocellular Carcinoma Cell Lines
Publicado: (2014)

TGF-β1/Smad3 Signaling Pathway Suppresses Cell Apoptosis in Cerebral Ischemic Stroke Rats
por: Zhu, Haiping, et al.
Publicado: (2017)

Curcumin in combination with homoharringtonine suppresses lymphoma cell growth by inhibiting the TGF-β/Smad3 signaling pathway
por: Zhang, Yu, et al.
Publicado: (2021)

Pirfenidone Alleviates Choroidal Neovascular Fibrosis through TGF-β/Smad Signaling Pathway
por: Gao, Chuang, et al.
Publicado: (2021)

Suppression of TGFβR-Smad3 pathway alleviates the syrinx induced by syringomyelia
por: Liu, Sumei, et al.
Publicado: (2023)

TGF‐β/Smad and Wnt/β‐catenin signaling pathways are involved in renal fibrosis and its therapies
por: Ying, Jialiang, et al.
Publicado: (2020)

Aspirin inhibits endometrial fibrosis by suppressing the TGF-β1-Smad2/Smad3 pathway in intrauterine adhesions
por: Zhang, Zihui, et al.
Publicado: (2020)

miR-425 suppresses EMT and the development of TNBC (triple-negative breast cancer) by targeting the TGF-β 1/SMAD 3 signaling pathway
por: Liu, Yingping, et al.
Publicado: (2018)

Recombinant TSG-6 protein inhibits the growth of capsule fibroblasts in frozen shoulder via suppressing the TGF-β/Smad2 signal pathway
por: Liu, Zhongfan, et al.
Publicado: (2021)

TGF-β1-Smad signaling pathways are not required for epidermal LC homeostasis
por: Li, Guihua, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_mptvvd65nekcfj9gfpjfemhtdd