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A Quantitative Modular Modeling Approach Reveals the Effects of Different A20 Feedback Implementations for the NF-kB Signaling Dynamics

Signaling pathways involve complex molecular interactions and are controled by non-linear regulatory mechanisms. If details of regulatory mechanisms are not fully elucidated, they can be implemented by different, equally reasonable mathematical representations in computational models. The study pres...

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Detalles Bibliográficos
Autores principales:	Mothes, Janina, Ipenberg, Inbal, Arslan, Seda Çöl, Benary, Uwe, Scheidereit, Claus, Wolf, Jana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402004/ https://www.ncbi.nlm.nih.gov/pubmed/32848849 http://dx.doi.org/10.3389/fphys.2020.00896

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