Cargando…

The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Mediated DNA Damage in the Kidney

In higher concentrations, the blood pressure regulating hormone angiotensin II leads to vasoconstriction, hypertension, and oxidative stress by activating NADPH oxidases which are a major enzymatic source of reactive oxygen species (ROS). With the help of knockout animals, the impact of the three pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimnol, Anna, Spicker, Nora, Balhorn, Ronja, Schröder, Katrin, Schupp, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402089/
https://www.ncbi.nlm.nih.gov/pubmed/32635630
http://dx.doi.org/10.3390/antiox9070586