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Targeting the MAPK/ERK and PI3K/AKT Signaling Pathways Affects NRF2, Trx and GSH Antioxidant Systems in Leukemia Cells

The mitogen-activated protein kinase (MAPK)/extracellular signal kinase (ERK) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) signal transduction pathways have been implicated in the pathogenesis of leukemia. The aim of this study was to investigate the effect of the combination of E...

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Detalles Bibliográficos
Autores principales: Jasek-Gajda, Ewa, Jurkowska, Halina, Jasińska, Małgorzata, Lis, Grzegorz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402140/
https://www.ncbi.nlm.nih.gov/pubmed/32709140
http://dx.doi.org/10.3390/antiox9070633