Susceptibility of SARS-CoV-2 to UV irradiation

The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10(6) TCID(50)/mL was completely inactivat...

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Detalles Bibliográficos
Autores principales: Heilingloh, Christiane Silke, Aufderhorst, Ulrich Wilhelm, Schipper, Leonie, Dittmer, Ulf, Witzke, Oliver, Yang, Dongliang, Zheng, Xin, Sutter, Kathrin, Trilling, Mirko, Alt, Mira, Steinmann, Eike, Krawczyk, Adalbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402275/
https://www.ncbi.nlm.nih.gov/pubmed/32763344
http://dx.doi.org/10.1016/j.ajic.2020.07.031
Descripción
Sumario:The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10(6) TCID(50)/mL was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1,048 mJ/cm(2). UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose.

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