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Susceptibility of SARS-CoV-2 to UV irradiation
The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10(6) TCID(50)/mL was completely inactivat...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402275/ https://www.ncbi.nlm.nih.gov/pubmed/32763344 http://dx.doi.org/10.1016/j.ajic.2020.07.031 |
| _version_ | 1783566723069247488 |
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| author | Heilingloh, Christiane Silke Aufderhorst, Ulrich Wilhelm Schipper, Leonie Dittmer, Ulf Witzke, Oliver Yang, Dongliang Zheng, Xin Sutter, Kathrin Trilling, Mirko Alt, Mira Steinmann, Eike Krawczyk, Adalbert |
| author_facet | Heilingloh, Christiane Silke Aufderhorst, Ulrich Wilhelm Schipper, Leonie Dittmer, Ulf Witzke, Oliver Yang, Dongliang Zheng, Xin Sutter, Kathrin Trilling, Mirko Alt, Mira Steinmann, Eike Krawczyk, Adalbert |
| author_sort | Heilingloh, Christiane Silke |
| collection | PubMed |
| description | The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10(6) TCID(50)/mL was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1,048 mJ/cm(2). UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose. |
| format | Online Article Text |
| id | pubmed-7402275 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-74022752020-08-05 Susceptibility of SARS-CoV-2 to UV irradiation Heilingloh, Christiane Silke Aufderhorst, Ulrich Wilhelm Schipper, Leonie Dittmer, Ulf Witzke, Oliver Yang, Dongliang Zheng, Xin Sutter, Kathrin Trilling, Mirko Alt, Mira Steinmann, Eike Krawczyk, Adalbert Am J Infect Control Brief Report The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10(6) TCID(50)/mL was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1,048 mJ/cm(2). UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose. Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2020-10 2020-08-04 /pmc/articles/PMC7402275/ /pubmed/32763344 http://dx.doi.org/10.1016/j.ajic.2020.07.031 Text en © 2020 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Brief Report Heilingloh, Christiane Silke Aufderhorst, Ulrich Wilhelm Schipper, Leonie Dittmer, Ulf Witzke, Oliver Yang, Dongliang Zheng, Xin Sutter, Kathrin Trilling, Mirko Alt, Mira Steinmann, Eike Krawczyk, Adalbert Susceptibility of SARS-CoV-2 to UV irradiation |
| title | Susceptibility of SARS-CoV-2 to UV irradiation |
| title_full | Susceptibility of SARS-CoV-2 to UV irradiation |
| title_fullStr | Susceptibility of SARS-CoV-2 to UV irradiation |
| title_full_unstemmed | Susceptibility of SARS-CoV-2 to UV irradiation |
| title_short | Susceptibility of SARS-CoV-2 to UV irradiation |
| title_sort | susceptibility of sars-cov-2 to uv irradiation |
| topic | Brief Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402275/ https://www.ncbi.nlm.nih.gov/pubmed/32763344 http://dx.doi.org/10.1016/j.ajic.2020.07.031 |
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