Bortezomib Plus Melphalan-Induced Cardiomyopathy Presenting as Sinus Tachycardia and Systolic Heart Failure

Chemotherapy-induced cardiotoxicity is a known condition, however, bortezomib and melphalan do not typically cause cardiotoxicity. With the rise in the use of newer chemotherapeutic agents, it is important to identify and understand the cardiac implications of chemotherapeutic agents. We present a c...

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Detalles Bibliográficos
Autores principales: Sampat, Parth J, Riaz, Sana, Martinez, Fidel, Aiello, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402422/
https://www.ncbi.nlm.nih.gov/pubmed/32775113
http://dx.doi.org/10.7759/cureus.9488
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author Sampat, Parth J
Riaz, Sana
Martinez, Fidel
Aiello, Dana
author_facet Sampat, Parth J
Riaz, Sana
Martinez, Fidel
Aiello, Dana
author_sort Sampat, Parth J
collection PubMed
description Chemotherapy-induced cardiotoxicity is a known condition, however, bortezomib and melphalan do not typically cause cardiotoxicity. With the rise in the use of newer chemotherapeutic agents, it is important to identify and understand the cardiac implications of chemotherapeutic agents. We present a case of a 70-year-old female with no known significant cardiac history presenting with partially reversible cardiomyopathy with initial presentation only being as sinus tachycardia.
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spelling pubmed-74024222020-08-06 Bortezomib Plus Melphalan-Induced Cardiomyopathy Presenting as Sinus Tachycardia and Systolic Heart Failure Sampat, Parth J Riaz, Sana Martinez, Fidel Aiello, Dana Cureus Cardiology Chemotherapy-induced cardiotoxicity is a known condition, however, bortezomib and melphalan do not typically cause cardiotoxicity. With the rise in the use of newer chemotherapeutic agents, it is important to identify and understand the cardiac implications of chemotherapeutic agents. We present a case of a 70-year-old female with no known significant cardiac history presenting with partially reversible cardiomyopathy with initial presentation only being as sinus tachycardia. Cureus 2020-07-31 /pmc/articles/PMC7402422/ /pubmed/32775113 http://dx.doi.org/10.7759/cureus.9488 Text en Copyright © 2020, Sampat et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Sampat, Parth J
Riaz, Sana
Martinez, Fidel
Aiello, Dana
Bortezomib Plus Melphalan-Induced Cardiomyopathy Presenting as Sinus Tachycardia and Systolic Heart Failure
title Bortezomib Plus Melphalan-Induced Cardiomyopathy Presenting as Sinus Tachycardia and Systolic Heart Failure
title_full Bortezomib Plus Melphalan-Induced Cardiomyopathy Presenting as Sinus Tachycardia and Systolic Heart Failure
title_fullStr Bortezomib Plus Melphalan-Induced Cardiomyopathy Presenting as Sinus Tachycardia and Systolic Heart Failure
title_full_unstemmed Bortezomib Plus Melphalan-Induced Cardiomyopathy Presenting as Sinus Tachycardia and Systolic Heart Failure
title_short Bortezomib Plus Melphalan-Induced Cardiomyopathy Presenting as Sinus Tachycardia and Systolic Heart Failure
title_sort bortezomib plus melphalan-induced cardiomyopathy presenting as sinus tachycardia and systolic heart failure
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402422/
https://www.ncbi.nlm.nih.gov/pubmed/32775113
http://dx.doi.org/10.7759/cureus.9488
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