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Inverse similarity and reliable negative samples for drug side-effect prediction
BACKGROUND: In silico prediction of potential drug side-effects is of crucial importance for drug development, since wet experimental identification of drug side-effects is expensive and time-consuming. Existing computational methods mainly focus on leveraging validated drug side-effect relations fo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402513/ https://www.ncbi.nlm.nih.gov/pubmed/30717666 http://dx.doi.org/10.1186/s12859-018-2563-x |