Cargando…

Host prion protein expression levels impact prion tropism for the spleen

Prions are pathogens formed from abnormal conformers (PrP(Sc)) of the host-encoded cellular prion protein (PrP(C)). PrP(Sc) conformation to disease phenotype relationships extensively vary among prion strains. In particular, prions exhibit a strain-dependent tropism for lymphoid tissues. Prions can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Béringue, Vincent, Tixador, Philippe, Andréoletti, Olivier, Reine, Fabienne, Castille, Johan, Laï, Thanh-Lan, Le Dur, Annick, Laisné, Aude, Herzog, Laetitia, Passet, Bruno, Rezaei, Human, Vilotte, Jean-Luc, Laude, Hubert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402522/ https://www.ncbi.nlm.nih.gov/pubmed/32702070 http://dx.doi.org/10.1371/journal.ppat.1008283

Ejemplares similares

Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures
por: Al-Dybiat, Iman, et al.
Publicado: (2019)

Transmission of Atypical Bovine Prions to Mice Transgenic for Human Prion Protein
por: Béringue, Vincent, et al.
Publicado: (2008)

Divergent prion strain evolution driven by PrP(C) expression level in transgenic mice
por: Le Dur, Annick, et al.
Publicado: (2017)

The Physical Relationship between Infectivity and Prion Protein Aggregates Is Strain-Dependent
por: Tixador, Philippe, et al.
Publicado: (2010)

Improving the Predictive Value of Prion Inactivation Validation Methods to Minimize the Risks of Iatrogenic Transmission With Medical Instruments
por: Moudjou, Mohammed, et al.
Publicado: (2020)

Quaternary Structure of Pathological Prion Protein as a Determining Factor of Strain-Specific Prion Replication Dynamics
por: Laferrière, Florent, et al.
Publicado: (2013)

Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification
por: Moudjou, Mohammed, et al.
Publicado: (2016)

Heterogeneity and Architecture of Pathological Prion Protein Assemblies: Time to Revisit the Molecular Basis of the Prion Replication Process?
por: Igel-Egalon, Angélique, et al.
Publicado: (2019)

The prion protein family: Looking outside the central nervous system
por: Passet, Bruno, et al.
Publicado: (2013)

The prion protein family: a view from the placenta
por: Makzhami, Samira, et al.
Publicado: (2014)

Highly Infectious Prions Generated by a Single Round of Microplate-Based Protein Misfolding Cyclic Amplification
por: Moudjou, Mohammed, et al.
Publicado: (2013)

Isolation from Cattle of a Prion Strain Distinct from That Causing Bovine Spongiform Encephalopathy
por: Béringue, Vincent, et al.
Publicado: (2006)

Emergence of two prion subtypes in ovine PrP transgenic mice infected with human MM2-cortical Creutzfeldt-Jakob disease prions
por: Chapuis, Jérôme, et al.
Publicado: (2016)

To develop with or without the prion protein
por: Halliez, Sophie, et al.
Publicado: (2014)

Prion potentiation after life-long dormancy in mice devoid of PrP
por: Martin, Davy, et al.
Publicado: (2021)

Transcriptomic Analysis Brings New Insight into the Biological Role of the Prion Protein during Mouse Embryogenesis
por: Khalifé, Manal, et al.
Publicado: (2011)

Prion Protein and Shadoo Are Involved in Overlapping Embryonic Pathways and Trophoblastic Development
por: Passet, Bruno, et al.
Publicado: (2012)

Prion protein localizes at the ciliary base during neural and cardiovascular development, and its depletion affects α-tubulin post-translational modifications
por: Halliez, Sophie, et al.
Publicado: (2015)

Prominent and Persistent Extraneural Infection in Human PrP Transgenic Mice Infected with Variant CJD
por: Béringue, Vincent, et al.
Publicado: (2008)

Reversible unfolding of infectious prion assemblies reveals the existence of an oligomeric elementary brick
por: Igel-Egalon, Angélique, et al.
Publicado: (2017)

Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases
por: Torrent, Joan, et al.
Publicado: (2015)

Early stage prion assembly involves two subpopulations with different quaternary structures and a secondary templating pathway
por: Igel-Egalon, Angélique, et al.
Publicado: (2019)

Prion Strains and Transmission Barrier Phenomena
por: Igel-Egalon, Angélique, et al.
Publicado: (2018)

Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouse
por: Chadi, Sead, et al.
Publicado: (2010)

Getting to the core of prion superstructural variability
por: Torrent, Joan, et al.
Publicado: (2015)

The Prion-like protein Shadoo is involved in mouse embryonic and mammary development and differentiation
por: Passet, Bruno, et al.
Publicado: (2020)

Prion assemblies: structural heterogeneity, mechanisms of formation, and role in species barrier
por: Igel, Angélique, et al.
Publicado: (2022)

In vitro Modeling of Prion Strain Tropism
por: Levavasseur, Etienne, et al.
Publicado: (2019)

Antihypertensive Drug Guanabenz Is Active In Vivo against both Yeast and Mammalian Prions
por: Tribouillard-Tanvier, Déborah, et al.
Publicado: (2008)

Pressure Reveals Unique Conformational Features in Prion Protein Fibril Diversity
por: Torrent, Joan, et al.
Publicado: (2019)

Biochemical insight into the prion protein family
por: Ciric, Danica, et al.
Publicado: (2015)

Studies on Prion Replication in Spleen
por: Raeber, Alex J., et al.
Publicado: (2001)

A specific role for PRND in goat foetal Leydig cells is suggested by prion family gene expression during gonad development in goats and mice
por: Allais‐Bonnet, Aurélie, et al.
Publicado: (2016)

Sheep and Goat BSE Propagate More Efficiently than Cattle BSE in Human PrP Transgenic Mice
por: Padilla, Danielle, et al.
Publicado: (2011)

Promiscuous functions of the prion protein family
por: Mouillet-Richard, Sophie, et al.
Publicado: (2015)

PrP(Sc) formation and clearance as determinants of prion tropism
por: Shikiya, Ronald A., et al.
Publicado: (2017)

Glycoform-Selective Prion Formation in Sporadic and Familial Forms of Prion Disease
por: Xiao, Xiangzhu, et al.
Publicado: (2013)

Porcine Prion Protein as a Paradigm of Limited Susceptibility to Prion Strain Propagation
por: Espinosa, Juan Carlos, et al.
Publicado: (2020)

Correction: Glycoform-Selective Prion Formation in Sporadic and Familial Forms of Prion Disease
por: Xiao, Xiangzhu, et al.
Publicado: (2013)

Prion disease modelled in Drosophila
por: Bujdoso, Raymond, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kac4kod93921h0iff3k18oafrv