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Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors
Maternal β-catenin activity is essential and critical for dorsal induction and its dorsal activation has been thoroughly studied. However, how the maternal β-catenin activity is suppressed in the nondorsal cells remains poorly understood. Nanog is known to play a central role for maintenance of the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402524/ https://www.ncbi.nlm.nih.gov/pubmed/32702011 http://dx.doi.org/10.1371/journal.pbio.3000561 |