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Antiproliferative Effects of Telotristat Ethyl in Patients with Neuroendocrine Tumors: The TELEACE Real-World Chart Review Study

PURPOSE: Neuroendocrine tumors (NETs) associated with carcinoid syndrome (CS) overproduce serotonin, mediated by tryptophan hydroxylase-1 (TPH1). The TPH inhibitor telotristat ethyl (TE) reduces peripheral serotonin and relieves CS symptoms. We conducted a real-world clinical practice study to explo...

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Detalles Bibliográficos
Autores principales: Morse, Michael A, Liu, Eric, Joish, Vijay N, Huynh, Lynn, Cheng, Mu, Duh, Mei Sheng, Seth, Kiernan, Lapuerta, Pablo, Metz, David C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402667/
https://www.ncbi.nlm.nih.gov/pubmed/32801896
http://dx.doi.org/10.2147/CMAR.S261257