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Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus
BACKGROUND: This study aimed to evaluate the scleral thickness and corneal parameters of patients with systemic lupus erythematosus (SLE). METHODS: Forty-seven eyes of 47 SLE patients and 44 eyes of healthy controls were included in this cross-sectional study. Anterior segment optical coherence tomo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402759/ https://www.ncbi.nlm.nih.gov/pubmed/32756168 http://dx.doi.org/10.1097/MD.0000000000021467 |
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author | Kaya, Hüseyin Karasu, Uğur Martin, Çiğdem Taşçi, Murat Pekel, Gökhan |
author_facet | Kaya, Hüseyin Karasu, Uğur Martin, Çiğdem Taşçi, Murat Pekel, Gökhan |
author_sort | Kaya, Hüseyin |
collection | PubMed |
description | BACKGROUND: This study aimed to evaluate the scleral thickness and corneal parameters of patients with systemic lupus erythematosus (SLE). METHODS: Forty-seven eyes of 47 SLE patients and 44 eyes of healthy controls were included in this cross-sectional study. Anterior segment optical coherence tomography (AS-OCT) was used to measure the corneal and scleral thickness. Scleral thickness (ST) was measured based upon the segmentation at 1000 to 5000 μm from the scleral spur. Pentacam HR was used to measure corneal parameters. RESULTS: There was no statistically significant difference between SLE group and control group according to age and sex (P > .05). The ST measurements at all distances from scleral spur were found to be thicker in patients with SLE (P < .05). Central corneal thickness (CCT), cornea volume (CV), corneal densitometry (CD), and peripheral corneal thickness (PCT) measurements were similar between the groups (P > .05). CONCLUSION: ST was thicker in SLE patients compared with healthy controls. AS-OCT seems helpful in selecting optimal sites for pharmaceutical or surgical intervention in SLE patients, since it shows thickness variations in anterior sclera. |
format | Online Article Text |
id | pubmed-7402759 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-74027592020-08-05 Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus Kaya, Hüseyin Karasu, Uğur Martin, Çiğdem Taşçi, Murat Pekel, Gökhan Medicine (Baltimore) 5800 BACKGROUND: This study aimed to evaluate the scleral thickness and corneal parameters of patients with systemic lupus erythematosus (SLE). METHODS: Forty-seven eyes of 47 SLE patients and 44 eyes of healthy controls were included in this cross-sectional study. Anterior segment optical coherence tomography (AS-OCT) was used to measure the corneal and scleral thickness. Scleral thickness (ST) was measured based upon the segmentation at 1000 to 5000 μm from the scleral spur. Pentacam HR was used to measure corneal parameters. RESULTS: There was no statistically significant difference between SLE group and control group according to age and sex (P > .05). The ST measurements at all distances from scleral spur were found to be thicker in patients with SLE (P < .05). Central corneal thickness (CCT), cornea volume (CV), corneal densitometry (CD), and peripheral corneal thickness (PCT) measurements were similar between the groups (P > .05). CONCLUSION: ST was thicker in SLE patients compared with healthy controls. AS-OCT seems helpful in selecting optimal sites for pharmaceutical or surgical intervention in SLE patients, since it shows thickness variations in anterior sclera. Wolters Kluwer Health 2020-07-31 /pmc/articles/PMC7402759/ /pubmed/32756168 http://dx.doi.org/10.1097/MD.0000000000021467 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | 5800 Kaya, Hüseyin Karasu, Uğur Martin, Çiğdem Taşçi, Murat Pekel, Gökhan Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus |
title | Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus |
title_full | Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus |
title_fullStr | Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus |
title_full_unstemmed | Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus |
title_short | Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus |
title_sort | measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus |
topic | 5800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402759/ https://www.ncbi.nlm.nih.gov/pubmed/32756168 http://dx.doi.org/10.1097/MD.0000000000021467 |
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