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Both Methylation and Copy Number Variation Participated in the Varied Expression of PRAME in Multiple Myeloma

PURPOSE: The cancer-testis antigen, which is a preferentially expressed antigen of melanoma (PRAME), is an ideal target for immunotherapy and cancer vaccines. Since the expression of this antigen is relevant to therapy responses, the heterogeneity in its expression and the underlying mechanism need...

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Detalles Bibliográficos
Autores principales:	Yang, Lu, Dao, Feng-Ting, Chang, Yan, Wang, Ya-Zhe, Li, Ling-Di, Chen, Wen-Min, Long, Ling-Yu, Liu, Yan-Rong, Lu, Jin, Liu, Kai-Yan, Qin, Ya-Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402861/ https://www.ncbi.nlm.nih.gov/pubmed/32801773 http://dx.doi.org/10.2147/OTT.S240979

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