A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy

Pulmonary tumor thrombotic microangiopathy (PTTM) is an acute, progressive, and fatal disease. PTTM manifests as subacute respiratory failure with pulmonary hypertension, progressive right-sided heart failure, and sudden death. An antemortem diagnosis of PTTM is very difficult to obtain, and many pa...

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Autores principales: Imakura, Takeshi, Tezuka, Toshifumi, Inayama, Mami, Miyamoto, Ryota, Abe, Akane, Otsuka, Kanako, Yoshida, Seiji, Kudo, Eiji, Haku, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402956/
https://www.ncbi.nlm.nih.gov/pubmed/32612065
http://dx.doi.org/10.2169/internalmedicine.3630-19
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author Imakura, Takeshi
Tezuka, Toshifumi
Inayama, Mami
Miyamoto, Ryota
Abe, Akane
Otsuka, Kanako
Yoshida, Seiji
Kudo, Eiji
Haku, Takashi
author_facet Imakura, Takeshi
Tezuka, Toshifumi
Inayama, Mami
Miyamoto, Ryota
Abe, Akane
Otsuka, Kanako
Yoshida, Seiji
Kudo, Eiji
Haku, Takashi
author_sort Imakura, Takeshi
collection PubMed
description Pulmonary tumor thrombotic microangiopathy (PTTM) is an acute, progressive, and fatal disease. PTTM manifests as subacute respiratory failure with pulmonary hypertension, progressive right-sided heart failure, and sudden death. An antemortem diagnosis of PTTM is very difficult to obtain, and many patients die within several weeks. We herein report a case of PTTM diagnosed based on a transbronchial lung biopsy. In this case, we finally diagnosed PTTM due to gastric cancer because of its histological identity. The patient was administered chemotherapy, including angiogenesis inhibitors, against gastric cancer at an early age and survived for a long time.
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spelling pubmed-74029562020-08-19 A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy Imakura, Takeshi Tezuka, Toshifumi Inayama, Mami Miyamoto, Ryota Abe, Akane Otsuka, Kanako Yoshida, Seiji Kudo, Eiji Haku, Takashi Intern Med Case Report Pulmonary tumor thrombotic microangiopathy (PTTM) is an acute, progressive, and fatal disease. PTTM manifests as subacute respiratory failure with pulmonary hypertension, progressive right-sided heart failure, and sudden death. An antemortem diagnosis of PTTM is very difficult to obtain, and many patients die within several weeks. We herein report a case of PTTM diagnosed based on a transbronchial lung biopsy. In this case, we finally diagnosed PTTM due to gastric cancer because of its histological identity. The patient was administered chemotherapy, including angiogenesis inhibitors, against gastric cancer at an early age and survived for a long time. The Japanese Society of Internal Medicine 2020-07-01 2020-07-01 /pmc/articles/PMC7402956/ /pubmed/32612065 http://dx.doi.org/10.2169/internalmedicine.3630-19 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Imakura, Takeshi
Tezuka, Toshifumi
Inayama, Mami
Miyamoto, Ryota
Abe, Akane
Otsuka, Kanako
Yoshida, Seiji
Kudo, Eiji
Haku, Takashi
A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy
title A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy
title_full A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy
title_fullStr A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy
title_full_unstemmed A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy
title_short A Long-term Survival Case of Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer Confirmed by the Early Diagnosis based on a Transbronchial Lung Biopsy
title_sort long-term survival case of pulmonary tumor thrombotic microangiopathy due to gastric cancer confirmed by the early diagnosis based on a transbronchial lung biopsy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402956/
https://www.ncbi.nlm.nih.gov/pubmed/32612065
http://dx.doi.org/10.2169/internalmedicine.3630-19
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