Rare Genotype of His/His in NUDT15 Codon 139 and Thiopurine-associated Adverse Events in a Case of Ulcerative Colitis

Thiopurine drugs are commonly used to treat immunologic diseases. However, the narrow therapeutic safety margin demands evidence-based precision medicine approaches. NUDT15 variants are associated with thiopurine-induced adverse events, particularly in Asians. We herein report a rare genotype of His...

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Detalles Bibliográficos
Autores principales: Tomiyoshi, Kei, Sato, Hiroki, Tominaga, Kentaro, Kawata, Yuzo, Okamoto, Daisuke, Kakuta, Yoichi, Yokoyama, Junji, Terai, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402964/
https://www.ncbi.nlm.nih.gov/pubmed/32269192
http://dx.doi.org/10.2169/internalmedicine.4261-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402964/
https://www.ncbi.nlm.nih.gov/pubmed/32269192
http://dx.doi.org/10.2169/internalmedicine.4261-19

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