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Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18–81 years—results from the LEAD cohort

BACKGROUND: Increasing attention has been drawn on the assessment of body composition phenotypes, since the distribution of soft tissue influences cardio-metabolic risk. Dual-energy X-ray absorptiometry (DXA) is a validated technique to assess body composition. European reference values from populat...

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Autores principales: Ofenheimer, Alina, Breyer-Kohansal, Robab, Hartl, Sylvia, Burghuber, Otto C., Krach, Florian, Schrott, Andrea, Wouters, Emiel F. M., Franssen, Frits M. E., Breyer, Marie-Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402993/
https://www.ncbi.nlm.nih.gov/pubmed/32123345
http://dx.doi.org/10.1038/s41430-020-0596-5
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author Ofenheimer, Alina
Breyer-Kohansal, Robab
Hartl, Sylvia
Burghuber, Otto C.
Krach, Florian
Schrott, Andrea
Wouters, Emiel F. M.
Franssen, Frits M. E.
Breyer, Marie-Kathrin
author_facet Ofenheimer, Alina
Breyer-Kohansal, Robab
Hartl, Sylvia
Burghuber, Otto C.
Krach, Florian
Schrott, Andrea
Wouters, Emiel F. M.
Franssen, Frits M. E.
Breyer, Marie-Kathrin
author_sort Ofenheimer, Alina
collection PubMed
description BACKGROUND: Increasing attention has been drawn on the assessment of body composition phenotypes, since the distribution of soft tissue influences cardio-metabolic risk. Dual-energy X-ray absorptiometry (DXA) is a validated technique to assess body composition. European reference values from population-based cohorts are rare. AIMS: To provide age- and sex-related reference values of body composition parameters and visceral adipose tissue (VAT) mass, and for lean mass index (LMI) with regard to fat mass index (FMI) quantities and BMI categories. METHODS: GE-Lunar Prodigy DXA scans of 10.894 participants, aged 18–81 years, recruited from 2011 to 2019 by the Austrian LEAD study, a population-based cohort study, have been used to construct reference curves using the LMS method. Parameters assessed are FMI, LMI, appendicular LMI, fat mass ratios android/gynoid and trunk/limbs, and VAT. RESULTS: All lean mass and fat mass parameters indicating central fat accumulation were higher in men, whereas other fat mass indices were higher in women. LMI differed between each FMI subgroup (low vs. normal, low vs. high, normal vs. high), and BMI category in all ages and LMI increased with FMI and BMI classes. VAT mass was higher in men compared with women and increased across all age groups within both sexes. CONCLUSION: The present study provides age- and sex-related reference values for European adults aged 18–81 years for body composition parameters and VAT mass for Lunar Prodigy DXA. In addition, this study reports LMI reference values with regard to fat mass quantities, showing a positive association with increasing FMI percentiles and BMI categories.
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spelling pubmed-74029932020-08-17 Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18–81 years—results from the LEAD cohort Ofenheimer, Alina Breyer-Kohansal, Robab Hartl, Sylvia Burghuber, Otto C. Krach, Florian Schrott, Andrea Wouters, Emiel F. M. Franssen, Frits M. E. Breyer, Marie-Kathrin Eur J Clin Nutr Article BACKGROUND: Increasing attention has been drawn on the assessment of body composition phenotypes, since the distribution of soft tissue influences cardio-metabolic risk. Dual-energy X-ray absorptiometry (DXA) is a validated technique to assess body composition. European reference values from population-based cohorts are rare. AIMS: To provide age- and sex-related reference values of body composition parameters and visceral adipose tissue (VAT) mass, and for lean mass index (LMI) with regard to fat mass index (FMI) quantities and BMI categories. METHODS: GE-Lunar Prodigy DXA scans of 10.894 participants, aged 18–81 years, recruited from 2011 to 2019 by the Austrian LEAD study, a population-based cohort study, have been used to construct reference curves using the LMS method. Parameters assessed are FMI, LMI, appendicular LMI, fat mass ratios android/gynoid and trunk/limbs, and VAT. RESULTS: All lean mass and fat mass parameters indicating central fat accumulation were higher in men, whereas other fat mass indices were higher in women. LMI differed between each FMI subgroup (low vs. normal, low vs. high, normal vs. high), and BMI category in all ages and LMI increased with FMI and BMI classes. VAT mass was higher in men compared with women and increased across all age groups within both sexes. CONCLUSION: The present study provides age- and sex-related reference values for European adults aged 18–81 years for body composition parameters and VAT mass for Lunar Prodigy DXA. In addition, this study reports LMI reference values with regard to fat mass quantities, showing a positive association with increasing FMI percentiles and BMI categories. Nature Publishing Group UK 2020-03-02 2020 /pmc/articles/PMC7402993/ /pubmed/32123345 http://dx.doi.org/10.1038/s41430-020-0596-5 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Ofenheimer, Alina
Breyer-Kohansal, Robab
Hartl, Sylvia
Burghuber, Otto C.
Krach, Florian
Schrott, Andrea
Wouters, Emiel F. M.
Franssen, Frits M. E.
Breyer, Marie-Kathrin
Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18–81 years—results from the LEAD cohort
title Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18–81 years—results from the LEAD cohort
title_full Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18–81 years—results from the LEAD cohort
title_fullStr Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18–81 years—results from the LEAD cohort
title_full_unstemmed Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18–81 years—results from the LEAD cohort
title_short Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18–81 years—results from the LEAD cohort
title_sort reference values of body composition parameters and visceral adipose tissue (vat) by dxa in adults aged 18–81 years—results from the lead cohort
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402993/
https://www.ncbi.nlm.nih.gov/pubmed/32123345
http://dx.doi.org/10.1038/s41430-020-0596-5
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