Cargando…

CD133 inhibition via autophagic degradation in pemetrexed-resistant lung cancer cells by GMI, a fungal immunomodulatory protein from Ganoderma microsporum

BACKGROUND: Adaptive drug resistance is an unfavourable prognostic factor in cancer therapy. Pemetrexed-resistant lung cancer cells possess high-metastatic ability via ERK–ZEB1 pathway-activated epithelial–mesenchymal transition. GMI is a fungal immunomodulatory protein that suppresses the survival...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsin, I-Lun, Chiu, Ling-Yen, Ou, Chu-Chyn, Wu, Wen-Jun, Sheu, Gwo-Tarng, Ko, Jiunn-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403151/ https://www.ncbi.nlm.nih.gov/pubmed/32448867 http://dx.doi.org/10.1038/s41416-020-0885-8

Ejemplares similares

The Protective Role of GMI, an Immunomodulatory Protein From Ganoderma microsporum, on 5-Fluorouracil-Induced Oral and Intestinal Mucositis
por: Li, Che-Hsing, et al.
Publicado: (2019)

Immunomodulatory Protein from Ganoderma microsporum Induces Pro-Death Autophagy through Akt-mTOR-p70S6K Pathway Inhibition in Multidrug Resistant Lung Cancer Cells
por: Chiu, Ling-Yen, et al.
Publicado: (2015)

GMI, an Immunomodulatory Peptide from Ganoderma microsporum, Restrains Periprosthetic Joint Infections via Modulating the Functions of Myeloid-Derived Suppressor Cells and Effector T Cells
por: Peng, Kuo-Ti, et al.
Publicado: (2021)

Ganoderma microsporum immunomodulatory protein, GMI, promotes C2C12 myoblast differentiation in vitro via upregulation of Tid1 and STAT3 acetylation
por: Teo, Wan-Huai, et al.
Publicado: (2020)

GMI, a protein from Ganoderma microsporum, induces ACE2 degradation to alleviate infection of SARS-CoV-2 Spike-pseudotyped virus
por: Yeh, Hsin, et al.
Publicado: (2022)

Safety assessment of the fungal immunomodulatory protein from Ganoderma microsporum (GMI) derived from engineered Pichia pastoris: Genetic toxicology, a 13-week oral gavage toxicity study, and an embryo-fetal developmental toxicity study in Sprague-Dawley rats
por: Fu, Hsu-Yuan, et al.
Publicado: (2022)

Plasma Endoglin is Associated with Favorable Outcome for Pemetrexed-Based Therapy in Advanced Non-Small Cell Lung Cancer
por: Li, Che-Hsing, et al.
Publicado: (2021)

High pemetrexed sensitivity of docetaxel-resistant A549 cells is mediated by TP53 status and downregulated thymidylate synthase
por: Kuo, Wei-Ting, et al.
Publicado: (2017)

Effect of Folic Acid and Vitamin B(12) on Pemetrexed Antifolate Chemotherapy in Nutrient Lung Cancer Cells
por: Yang, Tsung-Ying, et al.
Publicado: (2013)

Efficacy of GMI, a fungal immunomodulatory protein, for head and neck cancer patients with chemotherapy-related oral mucositis: An open-labeled prospective single-arm study
por: Lu, Hsueh-Ju, et al.
Publicado: (2022)

Polysaccharide of Ganoderma lucidum Ameliorates Cachectic Myopathy Induced by the Combination Cisplatin plus Docetaxel in Mice
por: Wu, Sung-Yu, et al.
Publicado: (2023)

GMI, a fungal immunomodulatory protein, ameliorates SARS-CoV-2 envelope protein-induced inflammation in macrophages via inhibition of MAPK pathway
por: Lin, Zhi-Hu, et al.
Publicado: (2023)

Ganoderma microsporum immunomodulatory protein acts as a multifunctional broad-spectrum antiviral against SARS-CoV-2 by interfering virus binding to the host cells and spike-mediated cell fusion
por: Ho, Ha Phan Thanh, et al.
Publicado: (2022)

The Effect of Ganoderma Microsporum immunomodulatory proteins on alleviating PM(2.5)-induced inflammatory responses in pregnant rats and fine particulate matter-induced neurological damage in the offsprings
por: Tseng, Chia-Yi, et al.
Publicado: (2019)

Optimization of magnetic properties and GMI effect of Thin Co-rich Microwires for GMI Microsensors
por: Gonzalez-Legarreta, Lorena, et al.
Publicado: (2020)

BMI1-Mediated Pemetrexed Resistance in Non-Small Cell Lung Cancer Cells Is Associated with Increased SP1 Activation and Cancer Stemness
por: Shen, Huan-Ting, et al.
Publicado: (2020)

miR-145-5p Targets Sp1 in Non-Small Cell Lung Cancer Cells and Links to BMI1 Induced Pemetrexed Resistance and Epithelial–Mesenchymal Transition
por: Chang, Wen-Wei, et al.
Publicado: (2022)

Recombinant Expression and Bioactivity Comparison of Four Typical Fungal Immunomodulatory Proteins from Three Main Ganoderma Species
por: Qu, Zheng-Wei, et al.
Publicado: (2018)

A Microsporum New to India
por: Maplestone, P. A., et al.
Publicado: (1939)

Inhibition of E-Selectin (GMI-1271) or E-selectin together with CXCR4 (GMI-1359) re-sensitizes multiple myeloma to therapy
por: Muz, Barbara, et al.
Publicado: (2019)

Ringworm vaccine; containing antigen from e.g. Microsporum canis, Microsporum gypsum or Trichophyton mentagrophytes
Publicado: (1991)

High Frequency Amplitude Detector for GMI Magnetic Sensors
por: Asfour, Aktham, et al.
Publicado: (2014)

Tinea incognito due to microsporum gypseum
por: Yu, Chunshui, et al.
Publicado: (2010)

Pseudomycetoma of the scalp caused by Microsporum canis()()
por: Ruiz, Ligia Rangel Barboza, et al.
Publicado: (2020)

Antitumor and Immunomodulatory Effects of Polysaccharides from Broken-Spore of Ganoderma lucidum
por: Wang, Peng-Yun, et al.
Publicado: (2012)

Antitumor and Immunomodulatory Activities of Ganoderma lucidum Polysaccharides in Glioma-Bearing Rats
por: Wang, Chunhua, et al.
Publicado: (2018)

Dermatophytosis caused by Microsporum canis and Microsporum gypseum in free-living Bradypus variegatus (Schiz, 1825) in the state of Pernambuco, Brazil
por: Xavier, Gileno Antônio Araújo, et al.
Publicado: (2008)

Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells
por: Hsin, Min-Chieh, et al.
Publicado: (2017)

Microsporum Canis Infection Mimics Pemphigus Erythematosus
por: Amano, Hiroo, et al.
Publicado: (2013)

Kennel Disinfectants for Microsporum canis and Trichophyton sp.
por: Moriello, Karen A.
Publicado: (2015)

Therapy and Antifungal Susceptibility Profile of Microsporum canis
por: Aneke, Chioma I., et al.
Publicado: (2018)

Human adaptation and diversification in the Microsporum canis complex
por: Zhou, Xin, et al.
Publicado: (2023)

Antifungal activity of Gracilaria corticata methanol extract against Trichophyton mentagrophytes, Microsporum canis, and Microsporum gypseum on rat dermatophytosis models
por: Shojaee, Asiyeh, et al.
Publicado: (2023)

Recombinant Ganoderma lucidum Immunomodulatory Protein Improves the Treatment for Chemotherapy-Induced Neutropenia
por: Lei, Xinhua, et al.
Publicado: (2020)

Low-cost Sensors Based on the GMI Effect in Recycled Transformer Cores
por: Jantaratana, Pongsakorn, et al.
Publicado: (2008)

Noise Modeling and Simulation of Giant Magnetic Impedance (GMI) Magnetic Sensor
por: Jin, Fang, et al.
Publicado: (2020)

Figurate erythematous lesion by Microsporum canis in immunosuppressed patient
por: Botelho, Karine Paschoal, et al.
Publicado: (2018)

Water Extract of Sporoderm-Broken Spores of Ganoderma lucidum Induces Osteosarcoma Apoptosis and Restricts Autophagic Flux
por: Zhang, Wenkan, et al.
Publicado: (2019)

Protective Effect of Ganoderma atrum Polysaccharide on Acrolein-Induced Apoptosis and Autophagic Flux in IEC-6 Cells
por: Wang, Yudan, et al.
Publicado: (2022)

Ling Zhi-8, a fungal immunomodulatory protein in Ganoderma lucidum, alleviates CPT-11-induced intestinal injury via restoring claudin-1 expression
por: Li, Ju-Pi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tamblb8cohmakep529am29k036