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RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology

BACKGROUND: Artificial intelligence (AI) is about to transform medical imaging. The Research Consortium for Medical Image Analysis (RECOMIA), a not-for-profit organisation, has developed an online platform to facilitate collaboration between medical researchers and AI researchers. The aim is to mini...

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Autores principales: Trägårdh, Elin, Borrelli, Pablo, Kaboteh, Reza, Gillberg, Tony, Ulén, Johannes, Enqvist, Olof, Edenbrandt, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403290/
https://www.ncbi.nlm.nih.gov/pubmed/32754893
http://dx.doi.org/10.1186/s40658-020-00316-9
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author Trägårdh, Elin
Borrelli, Pablo
Kaboteh, Reza
Gillberg, Tony
Ulén, Johannes
Enqvist, Olof
Edenbrandt, Lars
author_facet Trägårdh, Elin
Borrelli, Pablo
Kaboteh, Reza
Gillberg, Tony
Ulén, Johannes
Enqvist, Olof
Edenbrandt, Lars
author_sort Trägårdh, Elin
collection PubMed
description BACKGROUND: Artificial intelligence (AI) is about to transform medical imaging. The Research Consortium for Medical Image Analysis (RECOMIA), a not-for-profit organisation, has developed an online platform to facilitate collaboration between medical researchers and AI researchers. The aim is to minimise the time and effort researchers need to spend on technical aspects, such as transfer, display, and annotation of images, as well as legal aspects, such as de-identification. The purpose of this article is to present the RECOMIA platform and its AI-based tools for organ segmentation in computed tomography (CT), which can be used for extraction of standardised uptake values from the corresponding positron emission tomography (PET) image. RESULTS: The RECOMIA platform includes modules for (1) local de-identification of medical images, (2) secure transfer of images to the cloud-based platform, (3) display functions available using a standard web browser, (4) tools for manual annotation of organs or pathology in the images, (5) deep learning-based tools for organ segmentation or other customised analyses, (6) tools for quantification of segmented volumes, and (7) an export function for the quantitative results. The AI-based tool for organ segmentation in CT currently handles 100 organs (77 bones and 23 soft tissue organs). The segmentation is based on two convolutional neural networks (CNNs): one network to handle organs with multiple similar instances, such as vertebrae and ribs, and one network for all other organs. The CNNs have been trained using CT studies from 339 patients. Experienced radiologists annotated organs in the CT studies. The performance of the segmentation tool, measured as mean Dice index on a manually annotated test set, with 10 representative organs, was 0.93 for all foreground voxels, and the mean Dice index over the organs were 0.86 (0.82 for the soft tissue organs and 0.90 for the bones). CONCLUSION: The paper presents a platform that provides deep learning-based tools that can perform basic organ segmentations in CT, which can then be used to automatically obtain the different measurement in the corresponding PET image. The RECOMIA platform is available on request at www.recomia.org for research purposes.
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spelling pubmed-74032902020-08-13 RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology Trägårdh, Elin Borrelli, Pablo Kaboteh, Reza Gillberg, Tony Ulén, Johannes Enqvist, Olof Edenbrandt, Lars EJNMMI Phys Original Research BACKGROUND: Artificial intelligence (AI) is about to transform medical imaging. The Research Consortium for Medical Image Analysis (RECOMIA), a not-for-profit organisation, has developed an online platform to facilitate collaboration between medical researchers and AI researchers. The aim is to minimise the time and effort researchers need to spend on technical aspects, such as transfer, display, and annotation of images, as well as legal aspects, such as de-identification. The purpose of this article is to present the RECOMIA platform and its AI-based tools for organ segmentation in computed tomography (CT), which can be used for extraction of standardised uptake values from the corresponding positron emission tomography (PET) image. RESULTS: The RECOMIA platform includes modules for (1) local de-identification of medical images, (2) secure transfer of images to the cloud-based platform, (3) display functions available using a standard web browser, (4) tools for manual annotation of organs or pathology in the images, (5) deep learning-based tools for organ segmentation or other customised analyses, (6) tools for quantification of segmented volumes, and (7) an export function for the quantitative results. The AI-based tool for organ segmentation in CT currently handles 100 organs (77 bones and 23 soft tissue organs). The segmentation is based on two convolutional neural networks (CNNs): one network to handle organs with multiple similar instances, such as vertebrae and ribs, and one network for all other organs. The CNNs have been trained using CT studies from 339 patients. Experienced radiologists annotated organs in the CT studies. The performance of the segmentation tool, measured as mean Dice index on a manually annotated test set, with 10 representative organs, was 0.93 for all foreground voxels, and the mean Dice index over the organs were 0.86 (0.82 for the soft tissue organs and 0.90 for the bones). CONCLUSION: The paper presents a platform that provides deep learning-based tools that can perform basic organ segmentations in CT, which can then be used to automatically obtain the different measurement in the corresponding PET image. The RECOMIA platform is available on request at www.recomia.org for research purposes. Springer International Publishing 2020-08-04 /pmc/articles/PMC7403290/ /pubmed/32754893 http://dx.doi.org/10.1186/s40658-020-00316-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Research
Trägårdh, Elin
Borrelli, Pablo
Kaboteh, Reza
Gillberg, Tony
Ulén, Johannes
Enqvist, Olof
Edenbrandt, Lars
RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology
title RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology
title_full RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology
title_fullStr RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology
title_full_unstemmed RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology
title_short RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology
title_sort recomia—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403290/
https://www.ncbi.nlm.nih.gov/pubmed/32754893
http://dx.doi.org/10.1186/s40658-020-00316-9
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