Exposed CendR Domain in Homing Peptide Yields Skin-Targeted Therapeutic in Epidermolysis Bullosa

Systemic skin-selective therapeutics would be a major advancement in the treatment of diseases affecting the entire skin, such as recessive dystrophic epidermolysis bullosa (RDEB), which is caused by mutations in the COL7A1 gene and manifests in transforming growth factor-β (TGF-β)-driven fibrosis a...

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Detalles Bibliográficos
Autores principales: Pemmari, Toini, Ivanova, Larisa, May, Ulrike, Lingasamy, Prakash, Tobi, Allan, Pasternack, Anja, Prince, Stuart, Ritvos, Olli, Makkapati, Shreya, Teesalu, Tambet, Cairo, Mitchell S., Järvinen, Tero A.H., Liao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403337/
https://www.ncbi.nlm.nih.gov/pubmed/32497513
http://dx.doi.org/10.1016/j.ymthe.2020.05.017

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