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Endpoint surrogacy in oncology Phase 3 randomised controlled trials
Endpoint surrogacy is an important concept in oncology trials. Using a surrogate endpoint like progression-free survival as the primary endpoint—instead of overall survival—would lead to a potential faster drug approval and therefore more cancer patients with an earlier opportunity to receive the ne...
Autores principales: | Zhang, Jianrong, Pilar, Meagan R., Wang, Xiaofei, Liu, Jingxia, Pang, Herbert, Brownson, Ross C., Colditz, Graham A., Liang, Wenhua, He, Jianxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403397/ https://www.ncbi.nlm.nih.gov/pubmed/32451466 http://dx.doi.org/10.1038/s41416-020-0896-5 |
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