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Mebendazole is unique among tubulin-active drugs in activating the MEK–ERK pathway

We recently showed that the anti-helminthic compound mebendazole (MBZ) has immunomodulating activity in monocyte/macrophage models and induces ERK signalling. In the present study we investigated whether MBZ induced ERK activation is shared by other tubulin binding agents (TBAs) and if it is observa...

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Detalles Bibliográficos
Autores principales:	Andersson, Claes R., Selvin, Tove, Blom, Kristin, Rubin, Jenny, Berglund, Malin, Jarvius, Malin, Lenhammar, Lena, Parrow, Vendela, Loskog, Angelica, Fryknäs, Mårten, Nygren, Peter, Larsson, Rolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403428/ https://www.ncbi.nlm.nih.gov/pubmed/32753665 http://dx.doi.org/10.1038/s41598-020-68986-0

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