Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection

Respiratory syncytial virus (RSV) remains the most common cause of lower respiratory tract infections in children worldwide. Development of a vaccine has been hindered by the risk of developing enhanced respiratory disease (ERD) upon natural exposure to the virus. Generation of higher quality neutra...

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Detalles Bibliográficos
Autores principales: Eichinger, Katherine M., Kosanovich, Jessica L., Gidwani, Sonal V., Zomback, Aaron, Lipp, Madeline A., Perkins, Timothy N., Oury, Tim D., Petrovsky, Nikolai, Marshall, Christopher P., Yondola, Mark A., Empey, Kerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403488/
https://www.ncbi.nlm.nih.gov/pubmed/32849580
http://dx.doi.org/10.3389/fimmu.2020.01673

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