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ADAM17-Mediated Shedding of Inflammatory Cytokines in Hypertension

The increase of Angiontesin-II (Ang-II), one of the key peptides of the renin-angiotensin system (RAS), and its binding to the Ang-II type 1 receptor (AT(1)R) during hypertension is a crucial mechanism leading to AD\AM17 activation. Among the reported membrane anchored proteins cleaved by ADAM17, im...

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Detalles Bibliográficos
Autores principales:	de Queiroz, Thyago M., Lakkappa, Navya, Lazartigues, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403492/ https://www.ncbi.nlm.nih.gov/pubmed/32848763 http://dx.doi.org/10.3389/fphar.2020.01154

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