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GenomegaMap: Within-Species Genome-Wide d(N)/d(S) Estimation from over 10,000 Genomes
The [Formula: see text] ratio provides evidence of adaptation or functional constraint in protein-coding genes by quantifying the relative excess or deficit of amino acid-replacing versus silent nucleotide variation. Inexpensive sequencing promises a better understanding of parameters, such as [Form...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403622/ https://www.ncbi.nlm.nih.gov/pubmed/32167543 http://dx.doi.org/10.1093/molbev/msaa069 |