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Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model

BACKGROUND: Symptomatic treatments of Alzheimer’s Disease (AD) with cholinesterase inhibitors and/or memantine are relatively ineffective and there is a need for new treatments targeting the underlying pathology of AD. In most of the failed disease-modifying trials, patients have been allowed to con...

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Detalles Bibliográficos
Autores principales:	Riedel, Gernot, Klein, Jochen, Niewiadomska, Grazyna, Kondak, Constantin, Schwab, Karima, Lauer, Dilyara, Magbagbeolu, Mandy, Steczkowska, Marta, Zadrozny, Maciej, Wydrych, Malgorzata, Cranston, Anna, Melis, Valeria, Santos, Renato X., Theuring, Franz, Harrington, Charles R., Wischik, Claude M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403648/ https://www.ncbi.nlm.nih.gov/pubmed/32091331 http://dx.doi.org/10.2174/1567205017666200224120926

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