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Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing

BACKGROUND: To investigate the CT changes of different clinical types of COVID-19 pneumonia. METHODS: This retrospective study included 50 patients with COVID-19 from 16 January 2020 to 25 February 2020. We analyzed the clinical characteristics, CT characteristics and the pneumonia involvement of th...

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Autores principales: Liu, Nian, He, Guanghong, Yang, Xiongxiong, Chen, Jianxin, Wu, Jie, Ma, Min, Lu, Wenying, Li, Qiang, Cheng, Tao, Huang, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403785/
https://www.ncbi.nlm.nih.gov/pubmed/32758155
http://dx.doi.org/10.1186/s12880-020-00491-2
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author Liu, Nian
He, Guanghong
Yang, Xiongxiong
Chen, Jianxin
Wu, Jie
Ma, Min
Lu, Wenying
Li, Qiang
Cheng, Tao
Huang, Xiaohua
author_facet Liu, Nian
He, Guanghong
Yang, Xiongxiong
Chen, Jianxin
Wu, Jie
Ma, Min
Lu, Wenying
Li, Qiang
Cheng, Tao
Huang, Xiaohua
author_sort Liu, Nian
collection PubMed
description BACKGROUND: To investigate the CT changes of different clinical types of COVID-19 pneumonia. METHODS: This retrospective study included 50 patients with COVID-19 from 16 January 2020 to 25 February 2020. We analyzed the clinical characteristics, CT characteristics and the pneumonia involvement of the patients between the moderate group and the severe and critical group, and the dynamic changes of severity with the CT follow-up time. RESULTS: There were differences in the CT severity score of the right lung in the initial CT, and total CT severity score in the initial and follow-up CT between the moderate group and the severe and critical group (all p < 0.05). There was a quadratic relationship between total CT severity score and CT follow-up time in the severe and critical group (r(2) = 0.137, p = 0.008), the total CT severity score peaked at the second follow-up CT. There was no correlation between total CT severity score and CT follow-up time in the moderate group (p > 0.05). There were no differences in the occurrence rate of CT characteristics in the initial CT between the two groups (all p > 0.05). There were differences in the occurrence rate of ground-glass opacity and crazy-paving pattern in the second follow-up CT, and pleural thickening or adhesion in the third follow-up CT between the two groups (all p < 0.05). CONCLUSIONS: The CT changes of COVID-19 pneumonia with different severity were different, and the extent of pneumonia involvement by CT can help to assess the severity of COVID-19 pneumonia rather than the initial CT characteristics.
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spelling pubmed-74037852020-08-05 Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing Liu, Nian He, Guanghong Yang, Xiongxiong Chen, Jianxin Wu, Jie Ma, Min Lu, Wenying Li, Qiang Cheng, Tao Huang, Xiaohua BMC Med Imaging Research Article BACKGROUND: To investigate the CT changes of different clinical types of COVID-19 pneumonia. METHODS: This retrospective study included 50 patients with COVID-19 from 16 January 2020 to 25 February 2020. We analyzed the clinical characteristics, CT characteristics and the pneumonia involvement of the patients between the moderate group and the severe and critical group, and the dynamic changes of severity with the CT follow-up time. RESULTS: There were differences in the CT severity score of the right lung in the initial CT, and total CT severity score in the initial and follow-up CT between the moderate group and the severe and critical group (all p < 0.05). There was a quadratic relationship between total CT severity score and CT follow-up time in the severe and critical group (r(2) = 0.137, p = 0.008), the total CT severity score peaked at the second follow-up CT. There was no correlation between total CT severity score and CT follow-up time in the moderate group (p > 0.05). There were no differences in the occurrence rate of CT characteristics in the initial CT between the two groups (all p > 0.05). There were differences in the occurrence rate of ground-glass opacity and crazy-paving pattern in the second follow-up CT, and pleural thickening or adhesion in the third follow-up CT between the two groups (all p < 0.05). CONCLUSIONS: The CT changes of COVID-19 pneumonia with different severity were different, and the extent of pneumonia involvement by CT can help to assess the severity of COVID-19 pneumonia rather than the initial CT characteristics. BioMed Central 2020-08-05 /pmc/articles/PMC7403785/ /pubmed/32758155 http://dx.doi.org/10.1186/s12880-020-00491-2 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Liu, Nian
He, Guanghong
Yang, Xiongxiong
Chen, Jianxin
Wu, Jie
Ma, Min
Lu, Wenying
Li, Qiang
Cheng, Tao
Huang, Xiaohua
Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing
title Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing
title_full Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing
title_fullStr Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing
title_full_unstemmed Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing
title_short Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing
title_sort dynamic changes of chest ct follow-up in coronavirus disease-19 (covid-19) pneumonia: relationship to clinical typing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403785/
https://www.ncbi.nlm.nih.gov/pubmed/32758155
http://dx.doi.org/10.1186/s12880-020-00491-2
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