Cargando…

Identification and validation of prognosis‐related DLX5 methylation as an epigenetic driver in myeloid neoplasms

The deregulated DLX gene family members DLX1/2/3/4/5/6 (DLXs) caused by DNA methylation has been demonstrated in various cancers with therapeutic target value. However, the potential role of DLXs methylation in myeloid neoplasms such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ting‐juan, Xu, Zi‐jun, Gu, Yu, Wen, Xiang‐mei, Ma, Ji‐chun, Zhang, Wei, Deng, Zhao‐qun, Leng, Jia‐yan, Qian, Jun, Lin, Jiang, Zhou, Jing‐dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403826/ https://www.ncbi.nlm.nih.gov/pubmed/32508046 http://dx.doi.org/10.1002/ctm2.29

Ejemplares similares

Genome-wide methylation sequencing identifies progression-related epigenetic drivers in myelodysplastic syndromes
por: Zhou, Jing-dong, et al.
Publicado: (2020)

DNA methylation-mediated differential expression of DLX4 isoforms has opposing roles in leukemogenesis
por: Zhou, Jing-dong, et al.
Publicado: (2022)

Identification and validation of obesity-related gene LEP methylation as a prognostic indicator in patients with acute myeloid leukemia
por: Zhang, Ting-juan, et al.
Publicado: (2021)

The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms
por: Schwartz, Jason R., et al.
Publicado: (2021)

Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasms
por: Zhang, Qi, et al.
Publicado: (2019)

SLC22A3 methylation-mediated gene silencing predicts adverse prognosis in acute myeloid leukemia
por: Gu, Yu, et al.
Publicado: (2022)

LncRNA HOTAIR impairs the prognosis of papillary thyroid cancer via regulating cellular malignancy and epigenetically suppressing DLX1
por: Kuo, Feng-Chih, et al.
Publicado: (2022)

Down-regulated lncRNA DLX6-AS1 inhibits tumorigenesis through STAT3 signaling pathway by suppressing CADM1 promoter methylation in liver cancer stem cells
por: Wu, Dong-Mei, et al.
Publicado: (2019)

Whole-Genome DNA Methylation Sequencing Reveals Epigenetic Changes in Myelodysplastic Syndromes
por: Zhou, Jing-dong, et al.
Publicado: (2022)

Serum Exosomal lncRNA DLX6-AS1 Is a Promising Biomarker for Prognosis Prediction of Cervical Cancer
por: Ding, Xian-zhen, et al.
Publicado: (2021)

Retraction Note: Down-regulated lncRNA DLX6-AS1 inhibits tumorigenesis through STAT3 signaling pathway by suppressing CADM1 promoter methylation in liver cancer stem cells
por: Wu, Dong-Mei, et al.
Publicado: (2022)

Dlx5 and Dlx6 can antagonize cell division at the G(1)/S checkpoint
por: MacKenzie, Rachel K., et al.
Publicado: (2019)

SOX30 methylation correlates with disease progression in patients with chronic myeloid leukemia
por: Zhang, Ting-Juan, et al.
Publicado: (2019)

Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border
por: Narboux-Neme, Nicolas, et al.
Publicado: (2019)

Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina
por: Zhang, Qi, et al.
Publicado: (2017)

Pegylated liposomal doxorubicin for myeloid neoplasms
por: Zhang, Cheng, et al.
Publicado: (2019)

EZH2 dysregulation: Potential biomarkers predicting prognosis and guiding treatment choice in acute myeloid leukaemia
por: Chu, Ming‐qiang, et al.
Publicado: (2019)

DLX5 expression is monoallelic and Dlx5 is up-regulated in the Mecp2-null frontal cortex
por: Miyano, Masaru, et al.
Publicado: (2008)

Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan
por: de Lombares, Camille, et al.
Publicado: (2019)

Protective effect of DLX6-AS1 silencing against cerebral ischemia/reperfusion induced impairments
por: Hu, Xiamin, et al.
Publicado: (2020)

Abnormal expression and methylation of PRR34‐AS1 are associated with adverse outcomes in acute myeloid leukemia
por: Nan, Fang‐yu, et al.
Publicado: (2021)

DLX Genes: Roles in Development and Cancer
por: Tan, Yinfei, et al.
Publicado: (2021)

Transitory expression of Dlx5 and Dlx6 in maxillary arch epithelial precursors is essential for upper jaw morphogenesis
por: Gitton, Yorick, et al.
Publicado: (2014)

H19 overexpression promotes leukemogenesis and predicts unfavorable prognosis in acute myeloid leukemia
por: Zhang, Ting-juan, et al.
Publicado: (2018)

Dental and periodontal phenotypes of Dlx2 overexpression in mice
por: Dai, Jiewen, et al.
Publicado: (2017)

DNA Methylation of Enhancer Elements in Myeloid Neoplasms: Think Outside the Promoters?
por: Ordoñez, Raquel, et al.
Publicado: (2019)

Overexpression of Dlx2 leads to postnatal condyle degradation
por: Dai, Jiewen, et al.
Publicado: (2016)

Expression and prognosis analysis of DNMT family in acute myeloid leukemia
por: Zhang, Ting-Juan, et al.
Publicado: (2020)

m6A regulator-based methylation modification patterns and characterization of tumor microenvironment in acute myeloid leukemia
por: Xu, Zi-Jun, et al.
Publicado: (2022)

Epigenetics in Myeloproliferative Neoplasms
por: McPherson, Suzanne, et al.
Publicado: (2017)

Epigenetics in myeloproliferative neoplasms
por: Greenfield, Graeme, et al.
Publicado: (2023)

DLX, the multiprocessor assembly for LEP/SPS controls
por: Van der Stok, P D V
Publicado: (1990)

Non-parsimonious evolution of hagfish Dlx genes
por: Fujimoto, Satoko, et al.
Publicado: (2013)

Hypermethylation of secreted frizzled-related proteins predicts poor prognosis in non-M3 acute myeloid leukemia
por: Guo, Hong, et al.
Publicado: (2017)

Dlx5 Is a Cell Autonomous Regulator of Chondrocyte Hypertrophy in Mice and Functionally Substitutes for Dlx6 during Endochondral Ossification
por: Zhu, Hui, et al.
Publicado: (2009)

Loss of dlx5a/dlx6a Locus Alters Non-Canonical Wnt Signaling and Meckel’s Cartilage Morphology
por: Yu, Emily P. Y., et al.
Publicado: (2023)

Next-Generation Sequencing Improves Diagnosis, Prognosis and Clinical Management of Myeloid Neoplasms
por: Carbonell, Diego, et al.
Publicado: (2019)

To Develop and Validate the Combination of RNA Methylation Regulators for the Prognosis of Patients with Gastric Cancer
por: Zhang, Jun, et al.
Publicado: (2020)

Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression
por: Uribe, Rosa A., et al.
Publicado: (2015)

Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity
por: Goldman, Samantha L., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_l8n1tcdo2f8crmhonc3ve4a2jt