Cargando…

LGR6 Promotes Tumor Proliferation and Metastasis through Wnt/β-Catenin Signaling in Triple-Negative Breast Cancer

Leucine-rich-repeat-containing G protein-coupled receptor 6 (LGR6) has been identified as the stem cell marker in multiple normal tissues and malignancies. Previous studies implicated paradoxical functions of LGR6 as a tumor-suppressor gene or oncogene given to the specific context. To explore the e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Yanan, Ou, Xueqi, Li, Xing, Zeng, Yan, Gao, Guanfeng, Lyu, Ning, Liu, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403884/ https://www.ncbi.nlm.nih.gov/pubmed/32775619 http://dx.doi.org/10.1016/j.omto.2020.06.020

Ejemplares similares

R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5
por: Ruffner, Heinz, et al.
Publicado: (2012)

LGR5 and BMI1 Increase Pig Intestinal Epithelial Cell Proliferation by Stimulating WNT/β-Catenin Signaling
por: Li, Xiang-Guang, et al.
Publicado: (2018)

LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/β-Catenin Signaling
por: Scannell, Christopher A., et al.
Publicado: (2013)

Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway
por: MIAO, JUNJIE, et al.
Publicado: (2015)

LGR6 activates the Wnt/β-catenin signaling pathway and forms a β-catenin/TCF7L2/LGR6 feedback loop in LGR6(high) cervical cancer stem cells
por: Feng, Qian, et al.
Publicado: (2021)

LGR5 promotes the proliferation and tumor formation of cervical cancer cells through the Wnt/β-catenin signaling pathway
por: Chen, Qing, et al.
Publicado: (2014)

LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling
por: Mancini, Alessandra, et al.
Publicado: (2020)

LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma
por: Vieira, Gabriella Cunha, et al.
Publicado: (2015)

WNT10B/β-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer
por: Wend, Peter, et al.
Publicado: (2013)

Silencing LGR6 Attenuates Stemness and Chemoresistance via Inhibiting Wnt/β-Catenin Signaling in Ovarian Cancer
por: Ruan, Xiaohong, et al.
Publicado: (2019)

Correction: LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma
por: Vieira, Gabriella Cunha, et al.
Publicado: (2017)

PTEN-mediated AKT/β-catenin signaling enhances the proliferation and expansion of Lgr5+ hepatocytes
por: Han, Jimin, et al.
Publicado: (2021)

Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer
por: Ryu, Won-Ji, et al.
Publicado: (2020)

AFAP1-AS1 Promotes Epithelial-Mesenchymal Transition and Tumorigenesis Through Wnt/β-Catenin Signaling Pathway in Triple-Negative Breast Cancer
por: Zhang, Kaiming, et al.
Publicado: (2018)

The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer
por: Fatima, Iram, et al.
Publicado: (2017)

Corrigendum: AFAP1-AS1 Promotes Epithelial-Mesenchymal Transition and Tumorigenesis Through Wnt/β-Catenin Signaling Pathway in Triple-Negative Breast Cancer
por: Zhang, Kaiming, et al.
Publicado: (2020)

ZNF671 Inhibits the Proliferation and Metastasis of NSCLC via the Wnt/β-Catenin Pathway
por: Zhan, Wei, et al.
Publicado: (2020)

Correction: The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer
por: Fatima, Iram, et al.
Publicado: (2018)

LGR5 enhances the osteoblastic differentiation of MC3T3-E1 cells through the Wnt/β-catenin pathway
por: Yu, Wei, et al.
Publicado: (2021)

LGR5 regulates gastric adenocarcinoma cell proliferation and invasion via activating Wnt signaling pathway
por: Wang, Xiangfei, et al.
Publicado: (2018)

Wnt-beta-catenin pathway signals metastasis-associated tumor cell phenotypes in triple negative breast cancers
por: De, Pradip, et al.
Publicado: (2016)

Preferential Inhibition of Wnt/β-Catenin Signaling by Novel Benzimidazole Compounds in Triple-Negative Breast Cancer
por: Gangrade, Abhishek, et al.
Publicado: (2018)

Wnt/β-Catenin Inhibition Disrupts Carboplatin Resistance in Isogenic Models of Triple-Negative Breast Cancer
por: Abreu de Oliveira, Willy Antoni, et al.
Publicado: (2021)

Role of microRNA/lncRNA Intertwined With the Wnt/β-Catenin Axis in Regulating the Pathogenesis of Triple-Negative Breast Cancer
por: Hu, Xue, et al.
Publicado: (2022)

NOP14 inhibits melanoma proliferation and metastasis by regulating Wnt/β-catenin signaling pathway
por: Li, Jingrong, et al.
Publicado: (2018)

HMGB1 Promotes the Proliferation and Metastasis of Lung Cancer by Activating the Wnt/β-Catenin Pathway
por: Wang, Xiao-hui, et al.
Publicado: (2020)

Lidocaine inhibits the proliferation and metastasis of epithelial ovarian cancer through the Wnt/β-catenin pathway
por: Sun, Mei, et al.
Publicado: (2021)

Correction: LGR5 regulates gastric adenocarcinoma cell proliferation and invasion via activating Wnt signaling pathway
por: Wang, Xiangfei, et al.
Publicado: (2019)

Immunoexpression of LGR4 and Β-Catenin in Gastric Cancer and Normal Gastric Mucosa
por: de Souza, Susana Moreira, et al.
Publicado: (2019)

Expression of LGR5 in mammary myoepithelial cells and in triple-negative breast cancers
por: Lee, Hyun Ju, et al.
Publicado: (2021)

LINC00052 Promotes Gastric Cancer Cell Proliferation and Metastasis via Activating the Wnt/β-Catenin Signaling Pathway
por: Shan, Yuqiang, et al.
Publicado: (2017)

Countering Triple Negative Breast Cancer via Impeding Wnt/β-Catenin Signaling, a Phytotherapeutic Approach
por: Arzi, Laleh, et al.
Publicado: (2022)

Downregulation of MMSET impairs breast cancer proliferation and metastasis through inhibiting Wnt/β-catenin signaling
por: Zhao, Xiaohui, et al.
Publicado: (2019)

Wnt and β-Catenin Signaling in the Bone Metastasis of Prostate Cancer
por: Kaplan, Zachary, et al.
Publicado: (2021)

Wnt signaling in triple negative breast cancer is associated with metastasis
por: Dey, Nandini, et al.
Publicado: (2013)

MiR-27a-3p Targeting GSK3β Promotes Triple-Negative Breast Cancer Proliferation and Migration Through Wnt/β-Catenin Pathway
por: Wu, Ruizhen, et al.
Publicado: (2020)

Daucosterol Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Wnt/β-Catenin Signaling
por: Zeng, Junquan, et al.
Publicado: (2017)

Niclosamide sensitizes triple-negative breast cancer cells to ionizing radiation in association with the inhibition of Wnt/β-catenin signaling
por: Yin, Lina, et al.
Publicado: (2016)

circFBXW7 Inhibits Malignant Progression by Sponging miR-197-3p and Encoding a 185-aa Protein in Triple-Negative Breast Cancer
por: Ye, Feng, et al.
Publicado: (2019)

Wnt signaling modulator DKK4 inhibits colorectal cancer metastasis through an AKT/Wnt/β-catenin negative feedback pathway
por: Liang, Junrong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4t2n2d0b7qhb3pinnne6t778oh