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Cationic Pillar[6]arene Induces Cell Apoptosis by Inhibiting Protein Tyrosine Phosphorylation Via Host–Guest Recognition

We reported for the first time that cationic pillar[6]arene (cPA6) could tightly bind to peptide polymer (MW~20–50 kDa), an artificial substrate for tyrosine (Tyr) phosphorylation, and efficiently inhibit Tyr protein phosphorylation through host–guest recognition. We synthesized a nanocomposite of b...

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Detalles Bibliográficos
Autores principales: Li, Can-Peng, Lu, Yu-Xun, Zi, Cheng-Ting, Zhao, Yu-Ting, Zhao, Hui, Zhang, Ya-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404071/
https://www.ncbi.nlm.nih.gov/pubmed/32679647
http://dx.doi.org/10.3390/ijms21144979

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