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Loss of miR-145-5p Causes Ceruloplasmin Interference with PHD-Iron Axis and HIF-2α Stabilization in Lung Adenocarcinoma-Mediated Angiogenesis
For decades, lung cancer has been the leading cause of cancer-related death worldwide. Hypoxia-inducible factors (HIFs) play critical roles in mediating lung cancer development and metastasis. The present study aims to clarify how HIF’s over-activation affects lung cancer angiogenesis not only in a...
Autores principales: | Tsai, Ying-Ming, Wu, Kuan-Li, Chang, Yung-Yun, Chang, Wei-An, Huang, Yung-Chi, Jian, Shu-Fang, Tsai, Pei-Hsun, Lin, Yi-Shiuan, Chong, Inn-Wen, Hung, Jen-Yu, Hsu, Ya-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404111/ https://www.ncbi.nlm.nih.gov/pubmed/32708433 http://dx.doi.org/10.3390/ijms21145081 |
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