Beyond the Genomic Mutation: Rethinking the Molecular Biomarkers of K-RAS Dependency in Pancreatic Cancers

Oncogenic v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (K-RAS) plays a key role in the development and maintenance of pancreatic ductal adenocarcinoma (PDAC). The targeting of K-RAS would be beneficial to treat tumors whose growth depends on active K-RAS. The analysis of K-RAS genomic mutati...

Descripción completa

Detalles Bibliográficos
Autores principales: Mottini, Carla, Cardone, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404119/
https://www.ncbi.nlm.nih.gov/pubmed/32708716
http://dx.doi.org/10.3390/ijms21145023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404119/
https://www.ncbi.nlm.nih.gov/pubmed/32708716
http://dx.doi.org/10.3390/ijms21145023

Ejemplares similares