Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components

Propolis is a natural resinous material produced by bees and has been used in folk medicines since ancient times. Due to it possessing a broad spectrum of biological activities, it has gained significant scientific and commercial interest over the last two decades. As a result of searching 122 publi...

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Detalles Bibliográficos
Autores principales: Tran, Trong D., Ogbourne, Steven M., Brooks, Peter R., Sánchez-Cruz, Norberto, Medina-Franco, José L., Quinn, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404124/
https://www.ncbi.nlm.nih.gov/pubmed/32679731
http://dx.doi.org/10.3390/ijms21144988
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author Tran, Trong D.
Ogbourne, Steven M.
Brooks, Peter R.
Sánchez-Cruz, Norberto
Medina-Franco, José L.
Quinn, Ronald J.
author_facet Tran, Trong D.
Ogbourne, Steven M.
Brooks, Peter R.
Sánchez-Cruz, Norberto
Medina-Franco, José L.
Quinn, Ronald J.
author_sort Tran, Trong D.
collection PubMed
description Propolis is a natural resinous material produced by bees and has been used in folk medicines since ancient times. Due to it possessing a broad spectrum of biological activities, it has gained significant scientific and commercial interest over the last two decades. As a result of searching 122 publications reported up to the end of 2019, we assembled a unique compound database consisting of 578 components isolated from both honey bee propolis and stingless bee propolis, and analyzed the chemical space and chemical diversity of these compounds. The results demonstrated that both honey bee propolis and stingless bee propolis are valuable sources for pharmaceutical and nutraceutical development.
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spelling pubmed-74041242020-08-11 Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components Tran, Trong D. Ogbourne, Steven M. Brooks, Peter R. Sánchez-Cruz, Norberto Medina-Franco, José L. Quinn, Ronald J. Int J Mol Sci Review Propolis is a natural resinous material produced by bees and has been used in folk medicines since ancient times. Due to it possessing a broad spectrum of biological activities, it has gained significant scientific and commercial interest over the last two decades. As a result of searching 122 publications reported up to the end of 2019, we assembled a unique compound database consisting of 578 components isolated from both honey bee propolis and stingless bee propolis, and analyzed the chemical space and chemical diversity of these compounds. The results demonstrated that both honey bee propolis and stingless bee propolis are valuable sources for pharmaceutical and nutraceutical development. MDPI 2020-07-15 /pmc/articles/PMC7404124/ /pubmed/32679731 http://dx.doi.org/10.3390/ijms21144988 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tran, Trong D.
Ogbourne, Steven M.
Brooks, Peter R.
Sánchez-Cruz, Norberto
Medina-Franco, José L.
Quinn, Ronald J.
Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components
title Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components
title_full Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components
title_fullStr Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components
title_full_unstemmed Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components
title_short Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components
title_sort lessons from exploring chemical space and chemical diversity of propolis components
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404124/
https://www.ncbi.nlm.nih.gov/pubmed/32679731
http://dx.doi.org/10.3390/ijms21144988
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