A 3D Cell Culture Model Identifies Wnt/β‐Catenin Mediated Inhibition of p53 as a Critical Step during Human Hepatocyte Regeneration

The liver is a highly regenerative organ. While mature hepatocytes under homeostatic conditions are largely quiescent, upon injury, they rapidly enter the cell cycle to recover the damaged tissue. In rodents, a variety of injury models have provided important insights into the molecular underpinning...

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Detalles Bibliográficos
Autores principales: Oliva‐Vilarnau, Nuria, Vorrink, Sabine U., Ingelman‐Sundberg, Magnus, Lauschke, Volker M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404138/
https://www.ncbi.nlm.nih.gov/pubmed/32775153
http://dx.doi.org/10.1002/advs.202000248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404138/
https://www.ncbi.nlm.nih.gov/pubmed/32775153
http://dx.doi.org/10.1002/advs.202000248

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