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ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer

In this study we investigated the use of cancer cell protein expression of ABCG2 to predict efficacy of systemic first-line irinotecan containing therapy in patients with metastatic colorectal cancer (mCRC). From a Danish national cohort, we identified 119 mCRC patients treated with irinotecan conta...

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Detalles Bibliográficos
Autores principales: Palshof, Jesper Andreas, Cederbye, Camilla Natasha, Høgdall, Estrid Vilma Solyom, Poulsen, Tim Svenstrup, Linnemann, Dorte, Nygaard, Sune Boris, Stenvang, Jan, Christensen, Ib Jarle, Jensen, Benny Vittrup, Pfeiffer, Per, Brünner, Nils, Yilmaz, Mette, Viuff, Birgitte Martine, Nielsen, Dorte Lisbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404184/
https://www.ncbi.nlm.nih.gov/pubmed/32708825
http://dx.doi.org/10.3390/ijms21145027