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Calmodulin-Cork Model of Gap Junction Channel Gating—One Molecule, Two Mechanisms
The Calmodulin-Cork gating model is based on evidence for the direct role of calmodulin (CaM) in channel gating. Indeed, chemical gating of cell-to-cell channels is sensitive to nanomolar cytosolic calcium concentrations [Ca(2+)](i). Calmodulin inhibitors and inhibition of CaM expression prevent che...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404200/ https://www.ncbi.nlm.nih.gov/pubmed/32668628 http://dx.doi.org/10.3390/ijms21144938 |