Deep Sequencing of Small RNAs from Neurosurgical Extracellular Vesicles Substantiates miR-486-3p as a Circulating Biomarker that Distinguishes Glioblastoma from Lower-Grade Astrocytoma Patients

Extracellular vesicles (EVs) play key roles in glioblastoma (GBM; astrocytoma grade IV) biology and are novel sources of biomarkers. EVs released from GBM tumors can cross the blood-brain-barrier into the periphery carrying GBM molecules, including small non-coding RNA (sncRNA). Biomarkers cargoed i...

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Detalles Bibliográficos
Autores principales: Hallal, Susannah, Ebrahim Khani, Saeideh, Wei, Heng, Lee, Maggie Yuk Ting, Sim, Hao-Wen, Sy, Joanne, Shivalingam, Brindha, Buckland, Michael E., Alexander-Kaufman, Kimberley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404297/
https://www.ncbi.nlm.nih.gov/pubmed/32668808
http://dx.doi.org/10.3390/ijms21144954

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