Pro-Fibrotic Phenotype in a Patient with Segmental Stiff Skin Syndrome via TGF-β Signaling Overactivation

Transforming growth factor β (TGF-β) superfamily signaling pathways are ubiquitous and essential for several cellular and physiological processes. The overexpression of TGF-β results in excessive fibrosis in multiple human disorders. Among them, stiff skin syndrome (SSS) is an ultrarare and untreata...

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Detalles Bibliográficos
Autores principales: Fusco, Carmela, Nardella, Grazia, Augello, Bartolomeo, Boccafoschi, Francesca, Palumbo, Orazio, Fusaro, Luca, Notarangelo, Angelantonio, Barbano, Raffaela, Parrella, Paola, Annicchiarico, Giuseppina, De Meco, Carmela, Micale, Lucia, Graziano, Paolo, Castori, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404389/
https://www.ncbi.nlm.nih.gov/pubmed/32698527
http://dx.doi.org/10.3390/ijms21145141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404389/
https://www.ncbi.nlm.nih.gov/pubmed/32698527
http://dx.doi.org/10.3390/ijms21145141

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